Motrin, tablets 250 mg 10 pcs

Pain after injuries and operations, Arthritis, Flu, Arthrosis, Back pain, Pain, Sciatica, Neck pain, Lumbago, Osteoarthritis, Headache, Neuralgia (nerve pain), Migraine, Toothache, Angina, Myalgia (muscle pain), Sore throat, Menstrual pain (algodysmenorrhea), Joint pain (arthralgia), Muscle pain (myalgia), Infectious diseasesMild to moderate pain syndrome: Neuralgia, ossalgia, myalgia, lumbo-ischialgia, post-traumatic pain syndrome (sprains and contusions) accompanied by inflammation, postoperative pain (in trauma, orthopedics, gynecology, maxillofacial surgery), headache, migraine, algodysmenorrhea, adnexitis, toothache.

Symptomatic pain therapy in diseases of the musculoskeletal system, including bursitis, tendovaginitis.

In combination therapy of infectious and inflammatory diseases of the ear, throat and nose with a pronounced pain syndrome (pharyngitis, tonsillitis, otitis).

Feverish conditions with flu and colds.

The drug is used for symptomatic therapy (to reduce pain, inflammation and elevated body temperature) and has no effect on the progression of the main disease.

Active ingredient

Composition

How to take, the dosage

Interaction

When treating with anticoagulants, it should be borne in mind that naproxen may increase bleeding time.

The drug should not be used concomitantly with other NSAIDs (increased risk of side effects).

When concomitant use with guidantoin derivatives, anticoagulants or other drugs that bind significantly to plasma proteins, the effect of these drugs may be potentiated.

Naproxen may decrease the antihypertensive effects of propranololol and other beta-adrenoblockers and may also increase the risk of renal failure associated with the use of ACE inhibitors.

Taking probenecid increases the plasma concentration of naproxen.

Cyclosporine increases the risk of renal failure.

Naproxen slows the excretion of methotrexate, phenytoin, sulfonamides, increasing the risk of their toxic effects.

Antacids containing magnesium and aluminum decrease absorption of naproxen
.

Special Instructions

Do not exceed the doses indicated in the instructions. To reduce the risk of gastrointestinal adverse events, use the lowest effective dose for the shortest course possible. If pain and fever persist or get worse, you should see your doctor.

Patients with bronchial asthma, with blood clotting disorders, and patients with hypersensitivity to other analgesics should consult a physician before taking naproxen.

With caution, patients with liver disease and renal failure should be prescribed. In patients with renal insufficiency, creatinine clearance should be monitored. In chronic alcoholic and other forms of liver cirrhosis, the concentration of unbound naproxen is increased, so lower doses are recommended for these patients.

Naproxen should not be taken with other anti-inflammatory and pain medications unless prescribed by a physician. Lower doses are also recommended for elderly patients. Naproxen should be avoided for 48 hours before surgery. If 17 corticosteroids need to be determined, the drug should be discontinued 48 hours before the study. Similarly, naproxen may affect the determination of 5-hydroxyindoleacetic acid in urine. The use of naproxen, as well as other drugs that block the synthesis of prostaglandins, may affect fertility, so it is not recommended for women planning to become pregnant.

Synopsis

Contraindications

Side effects

Overdose

Significant overdose of the drug may be characterized by drowsiness, dyspeptic disorders (heartburn, nausea and vomiting, abdominal pain), weakness, tinnitus, irritability, in severe cases – bloody vomiting, melena, impaired consciousness, seizures and renal failure.

Treatment: gastric lavage, activated charcoal and symptomatic therapy: antacids, H2-histamine receptor blockers, proton pump inhibitors. Hemodialysis is ineffective.

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