Milk thistle oil with selenium Biocor, 250 ml

Milk thistle interacts with free radicals in the liver and reduces their toxicity.

By interrupting the process of lipid peroxidation it prevents further destruction of cell structures.

In damaged hepatocytes it stimulates synthesis of structural and functional proteins and phospholipids (due to specific stimulation of RNA-polymerase A), stabilizes cell membranes, prevents loss of cellular components and intracellular enzymes (transaminases) and accelerates regeneration of liver cells.

Inhibits penetration into cells of some hepatotoxic substances (poisons of the pale grebes fungus). It is subjected to enterohepatic circulation. It is metabolized in the liver by conjugation.

Extracted mainly with bile in the form of glucuronides and sulfates, to a small extent with urine. It does not accumulate. After repeated oral administration of 140 mg 3 times a day a stable concentration is reached.

It improves general state of patients with liver diseases, decreases subjective complaints, normalizes laboratory indexes (activity of transaminases, gamma-glutamyltransferase, alkaline phosphate, bilirubin level).

Long-term use significantly increases survival rate of patients with cirrhosis.

Indications

Composition

milk thistle extract (silymarin) + excipients

How to take, the dosage

Adults and children over 12 years: 0.5 teaspoons 2 times a day with meals. The course of treatment is 30 days.

Interaction

When using milk thistle together with oral hormonal contraceptives and drugs intended for hormone replacement therapy, it is possible to reduce the effects of the latter.

Silymarin may increase the effects of diazepam, alprazolam, ketoconazole, lovastatin, vinblastine due to its inhibitory action on microsomal enzymes of cytochrome P450 system.

Contraindications

Hypersensitivity