Biocor Milk thistle tablets, 60 pcs.

Milk thistle interacts with free radicals in the liver and reduces their toxicity.

By interrupting the process of lipid peroxidation, it prevents further destruction of cell structures.

In damaged hepatocytes it stimulates synthesis of structural and functional proteins and phospholipids (due to specific stimulation of RNA-polymerase A), stabilizes cell membranes, prevents loss of cellular components and intracellular enzymes (transaminases), accelerates regeneration of liver cells. Inhibits penetration into cells of some hepatotoxic substances (poisons of the pale grebes mushroom).

It is subjected to enterohepatic circulation. It is metabolized in the liver by conjugation. It is excreted mainly with bile in the form of glucuronides and sulfates and to a small extent with urine.

It does not cumulate. Stable concentrations are reached after repeated oral administration of 140 mg 3 times daily.

It improves the general state of patients with liver diseases, decreases subjective complaints, normalizes laboratory indexes (activity of transaminases, gamma-glutamyltransferase, alkaline phosphate, bilirubin level).

Long-term use significantly increases survival rate of patients with cirrhosis.

Indications

• toxic liver damage (alcoholism, intoxication with halogen containing hydrocarbons, compounds of heavy metals, drug-induced liver damage) and their prevention;
• chronic hepatitis;
• Hepatic cirrhosis (as part of complex therapy);
• states after infectious and toxic hepatitis, liver dystrophy and fatty infiltration;
• correction of lipid metabolism disorders.

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Composition

Milk thistle meal “Biocor”,

maltodextrin,

oat grass extract dry,

sugar,

calcium stearate,

silicon dioxide.

How to take, the dosage

Adults and children over 12 years: 0.5 teaspoons 2 times a day with meals. The course of treatment is 30 days.

Interaction

When using milk thistle together with oral hormonal contraceptives and drugs intended for hormone replacement therapy, it is possible to reduce the effects of the latter.

Silimarin may increase the effects of diazepam, alprazolam, ketoconazole, lovastatin, vinblastine due to its inhibitory action on microsomal enzymes of cytochrome P450 system.

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Contraindications

Hypersensitivity

Side effects

• diarrhea;
• allergic reactions;
• children under 12 years of age;
• high sensitivity to the components of the drug.

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