Melarena, 3 mg 10 pcs
€11.74 €9.79
Synthetic analogue of the pineal body hormone (epiphysis) melatonin; has adaptogenic, sedative, and hypnotic effects. It normalizes circadian rhythms.
Increases the concentration of gamma-aminobutyric acid (GABA) and serotonin in the midbrain and hypothalamus, changes the activity of pyridoxal kinase, involved in the synthesis of GABA, dopamine and serotonin.
Regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature, has a positive effect on the intellectual and mental functions of the brain, on the emotional and personality sphere.
It promotes the organization of the biological rhythm and the normalization of night sleep.
It improves the quality of sleep, accelerates falling asleep, reduces the number of night awakenings, improves the sense of well-being after the morning awakening, does not cause the feeling of dullness, weariness and fatigue upon awakening.
Makes dreams more vivid and emotionally charged.
Adapts the body to rapid change of time zones, reduces stress reactions, regulates neuroendocrine functions.
Adapts the body of people sensitive to changes in weather conditions. It shows immune-stimulating and antioxidant properties.
Inhibits secretion of gonadotropins, to a lesser extent – other adenohypophysis hormones (corticotropin, thyroid hormone, somatotropic hormone). It is not addictive and not dependent.
When administered orally it is quickly and completely absorbed, easily passes through histohematic barriers including the blood-brain barrier. It has a short half-life.
Indications
Weakness and fatigue, Irritability, Change of time zones, Meteosensitivity, Insomnia, Depression
- Desynchronosis (violation of the normal circadian rhythm) due to rapid movement between the time zones of the Earth; in violation of the light regime, including people engaged in shift work or rotational work.
- Sleep disorders.
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Active ingredient
Melatonin
Composition
1 film-coated tablet contains:
The active ingredient
Melatonin – 0.30 mg or 3.00 mg;
Associates:
Calcium hydrophosphate dihydrate – 67.37/ 64.67 mg,
Microcrystalline cellulose – 25.00/ 25.00 mg,
Croscarmellose sodium – 2.00/ 2.00 mg,
Povidon-K25 – 3,33/ 3,33 mg,
Colloidal silica – 0,50/ 0,50 mg,
Talc – 1,00/ 1,00 mg,
Calcium stearate – 0,50/ 0,50 mg;
Covering:
For a dosage of 0.3 mg:
Hypromellose 62.50%,
Triethylcitrate 12.50%,
Titanium Dioxide 25.00% – 3.00 mg;
For 3 mg dosage
Hypromellose 62.50%,
Macrogol-400 12.50%,
Titanium dioxide 24,21%,
Aluminum varnish FD&C blue No. 2 (12-14%) 0,28%,
Aluminum varnish FD&C blue No. 1 (11-13%) 0.48%,
Quinoline yellow varnish 0.02%,
Iron oxide black dye 0.01% – 3.00 mg.
How to take, the dosage
Orally.
In case of sleep disorders, desynchronosis – 1 tablet once a day 30-40 minutes before bedtime.
When used as an adaptogen when changing time zones 1 day before the flight and during the next 2-5 days 1 tablet 30-40 minutes before sleep.
The maximum daily dose is 6 mg.
Interaction
Incompatible with monoamine oxidase inhibitors (MAOIs), glucocorticosteroids, cyclosporine.
Increases the effect of drugs that depress the central nervous system and beta-adrenoblockers.
It is not recommended to take simultaneously with nonsteroidal anti-inflammatory drugs (NSAIDs).
It is not recommended to take together with hormonal drugs.
Special Instructions
During the use of the drug Melaren® it is recommended to avoid being in bright light.
Women who want to get pregnant should be informed about the weak contraceptive effect of the drug.
Effect on the ability to drive vehicles and mechanisms
During the treatment, caution should be exercised when driving vehicles and performing other potentially dangerous activities that require increased concentration and rapid psychomotor reactions.
Contraindications
Hypersensitivity to melatonin and other drug components; autoimmune diseases, allergic diseases; lymphogranulematosis, leukemia, lymphoma, myeloma, epilepsy, diabetes, chronic renal failure;
severe renal failure (for 3 mg dosage); pregnancy, breast-feeding; age under 18 years (effectiveness and safety of use are unknown).
Side effects
Allergic reactions to components of the drug, headache, nausea, vomiting, diarrhea, morning drowsiness, swelling (usually in the first week of use).
Overdose
There are no data on cases of melatonin overdose.
A dose-dependent adverse reactions may increase.
Treatment: gastric lavage, symptomatic therapy.
Similarities
Melaxen, Sonnovan, Melarena, Melatonin, Wellson, Strengthen Your Immunity by Evalar
Weight | 0.010 kg |
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Shelf life | 2 years. Do not use the drug after the expiration date stated on the package. |
Conditions of storage | In a dry, light-protected place at a temperature no higher than 25 ° C. Keep out of reach of children. |
Manufacturer | Chemopharm LLC, Russia |
Medication form | pills |
Brand | Chemopharm LLC |
Other forms…
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