Mardil Zinc Max with microcapillaries, 0.5 ml

When used topically and locally on the affected areas of the skin the drug is able to interrupt the growth and activity of pathologically changed cells, including benign skin neoplasms through anticoagulation, dehydration and devitalization.

When used on the affected areas the drug leads to fixation with subsequent mummification of pathologically changed tissue. Mummified scabs detach only after complete reepithelization spontaneously in 2 – 3 weeks.

Indications

• denign skin lesions of viral origin.
• denign epithelial skin tumors,
• denign melanocytic skin tumors.

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Active ingredient

Zinc 2-chloropropionate solution 1.5% in 2-chloropropionic acid

Composition

Composition per 1 ml:

Active ingredient:

Mardil Zinc® semi-finished solution (1.5% solution of zinc chlorpropionate in 2-chloropropionic acid) – 0.5 ml;

Auxiliary substance:

purified water – up to 1 ml.

How to take, the dosage

For external use.

The treatment process is carried out on an outpatient basis under the supervision of a physician. The procedure does not require anesthesia. The drug is applied with a plastic spatula with a cotton swab or using a glass capillary on the surface of the formation previously degreased with 70% alcohol. Treatment is carried out in 1-3 applications until the appearance of whitish-gray staining.

The discoloration of the tissue occurs within 2-3 minutes after application of the drug. In the presence of pronounced hyperkeratosis within 5-7 minutes. At the same time, there is a change in the consistency of the neoplasm to a denser one. The dosage of the drug depends on the type of density size and severity of hyperkeratosis and can be from 002 ml to 02 ml.

The maximum daily dose is 02 ml.

The number of treatment sessions varies from 1 session (flat warts) up to 3-4 (plantar warts) till the complete disappearance of the element with the interval between the sessions of at least 24 hours. After the application of Mardil Zinc® Max a transient band of hyperemia and edema is observed around the neoplasm, which disappears without a trace in 25-40 minutes after the end of the procedure. No additional therapeutic measures are required after application.

The next day after application, the pathological focus mummifies, acquires a dark brown color and sharply decreases in size. The mummified scabs detach only after complete epithelialization, spontaneously after 2-3 weeks. Healing proceeds without complications especially in the absence of secondary infection without leaving significant scars and deformations of adjacent tissues or impairment of functions of organs.

Local. Treatment of anogenital warts.

The treatment is carried out on an outpatient basis under the supervision of a doctor, the procedure does not require anesthesia. The drug is applied with a universal probe or applicator. After applying the drug the color of the tissue changes to a whitish-gray coloration. The volume of the applied preparation depends on the size of the formation and the area of the lesion and can be from 002 ml to 02 ml. A maximum of 2-3 lesion sites with a total area of up to 3 sq.cm can be treated during each session.

The maximum daily dose is 02 ml.

In case of more extensive lesions, treatment with the drug should be carried out in several stages with an interval of at least 24 hours. When applying Mardil Zinc® Max a slight swelling of the mucous membrane occurs. Within 2-3 days after using the drug there is detachment of necrotic tissues. Complete regeneration is observed within 10-14 days. With large anogenital warts in case of incomplete necrosis, it is possible to reapply the drug in 5-7 days.

Interaction

Interaction of the drug with other drugs for external action has not been established.

Special Instructions

Handle with care.

The bottle should be shaken before opening and the solution at the top of the bottle should be moved to the bottom. The opened vial must be held in a vertical position.

Mardil Zinc® Max contains acid. Avoid contact of the product with healthy skin or mucosa. If accidental contact of Mardyl Zinc® Max with healthy skin or mucosa occurs, remove the product as soon as possible using a cotton swab moistened with water. Special precautions should be taken when treating skin lesions near the eye area.

Avoid getting the product in the eyes! If accidental contact of Mardil Zinc® Max into the eyes occurs, rinse immediately with plenty of water and 1% sodium bicarbonate solution and then seek medical attention.

The mummified scab should not be removed by scraping or mechanical means. The scab must detach from healthy skin or mucous membranes on its own, otherwise tissue healing and scarring may be impaired. Until complete healing of the skin or mucous membranes it is not recommended to swim in swimming pools and open reservoirs, as well as avoid direct sunlight and ultraviolet radiation. On the day of treatment, it is recommended to limit water procedures. It is advisable to avoid traumatization and contamination of the treated lesion until complete epithelialization.

Disposal of used vials: Leftover product residue should be rinsed under running water before discarding the vial. You can dispose of the empty bottle in a waste container.

Contraindications

• malignant neoplasms of the skin and mucous membranes,
• explicit tendency to form keloids,
• pregnancy,

breastfeeding period,

• age under 18 years of age,

high sensitivity of the drug.

• pregnancy,
• breast-feeding period,
• age below 18 years of age,
• high sensitivity to the components of the product.

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Side effects

The use of Mardil Zinc® Max in rare cases may lead to changes in skin pigmentation and formation of superficial skin scars.

With the normal course of the epithelization process, the absence of secondary infection and independent separation of mummified scabs the probability of such negative effects is extremely low.

Tissue edema may be observed very rarely in case of individual sensitivity to the drug components allergic reactions in the form of skin itching are possible.

Overdose

Erosion may occur if the product is used incorrectly. In order to prevent acid burns, the drug should be rinsed off with running water. Healing can occur on its own without the use of additional medications or with the use of wound healing agents.

Pregnancy use

Studies on the possible effects of the drug on the body of pregnant women and nursing mothers have not been conducted so far. Treatment in this category of patients should be administered only when the potential benefit to the mother outweighs the possible risk to the fetus or child.