Mardil Selenium, 0.5 ml with microcapillaries 5 pcs

Pharmacokinetics:

Absorption of the active substances and their systemic effects on the body have not been found when applying Mardil Selenium to the affected areas of the skin.

Pharmacodynamics:

Mardyl Selenium is a solution of selenic acid (0.45% in terms of selenium) in 70% 2.2-dichloropropionic acid. When applied externally to the affected areas of the skin, the drug is able to interrupt the growth and activity of pathologically changed cells, including benign skin neoplasms and malignant non-metastatic skin tumors through angioagulation, dehydration and devitalization.

The action of the drug on the affected area of the skin provides immediate lifetime fixation with subsequent mummification of the pathologically changed tissue with which the drug comes into contact. The immediate effect of the drug is expressed in the appearance of a characteristic whitish-gray or grayish color.

Devitalized tissue after exposure to the drug dehydrates and, as it mummifies, takes on a dark brown coloration. The resulting mummified scab peels off after complete re-epithelialization, after 2-4 weeks Healing is uneventful, especially in the absence of secondary infection, leaving no significant scars and scars, deformities of adjacent tissues or organ dysfunction.

Indications

external treatment of vascular benign neoplasms (senile hemangioma, angiokeratoma, angiomatous nevus);
external treatment of benign skin tumors (low-pigment and non-pigment nevi, papillomatous nevi, cutaneous horn, seborrheic keratosis and other keratoses);
external treatment of non-metastatic malignant skin tumors (basal cell carcinoma, stage 1).
external treatment of benign skin formations of viral origin (common warts, plantar warts, flat warts, papillomas);

Pharmacological effect

Pharmacokinetics:

When applying the drug Mardil Selenium to the affected areas of the skin, absorption of active substances and their systemic effect on the body were not detected.

Pharmacodynamics:

Mardil Selenium is a solution of selenous acid (0.45% in terms of selenium) in 70% 2.2-dichloropropionic acid. When applied externally to affected areas of the skin, the drug can interrupt the growth and vital activity of pathologically altered cells, incl. benign skin tumors and malignant non-metastasizing skin tumors through angiocoagulation, dehydration and devitalization.

The effect of the drug on the affected area of ​​the skin provides direct intravital fixation with subsequent mummification of the pathologically altered tissue with which the drug comes into contact. The immediate effect of the drug is expressed in the appearance of a characteristic whitish-gray or grayish color.

The tissue devitalized after exposure to the drug is dehydrated and, as it mummifies, acquires a dark brown color. The resulting mummified scab peels off after complete re-epithelialization, after 2-4 weeks. Healing proceeds without complications, especially in the absence of a secondary infection, without leaving significant scars, deformations of adjacent tissues or dysfunction of organs.

Special instructions

Handle with care.

Before opening, shake the bottle and move the solution that gets into the top of the bottle to the bottom. The opened bottle must be in a strictly vertical position.

Mardil Selenium contains acid. Avoid contact of the drug with healthy skin or mucous membrane. If Mardil Selenium accidentally comes into contact with healthy skin or mucous membrane, it is necessary to remove the drug as quickly as possible using a cotton swab moistened with water. When treating affected skin areas near the eye area, special precautions should be taken. Avoid getting the drug in your eyes. If Mardil Selenium accidentally gets into your eyes, you should immediately rinse them with plenty of water and 1% sodium bicarbonate solution, and then consult a doctor.

A mummified scab should not be removed by scraping or using mechanical means. The scab must separate from the healthy skin on its own, otherwise tissue healing processes may be disrupted and scars may form. Until complete healing of the skin is achieved, it is not recommended to swim in pools or open water, and exposure to direct sunlight and ultraviolet radiation should be avoided. On the day of treatment, it is recommended to limit water treatments. It is advisable to avoid trauma and contamination of the treated pathological focus until complete epithelialization.

Disposal of used bottles: before discarding the bottle, the remaining drug should be washed off in running water. The empty bottle can be thrown into the trash container.

Composition

Active ingredient:

selenous acid solution 0.9% in 90% 2,2-dichloropropionic acid 0.78 g;

Excipients:

purified water

Contraindications

pronounced tendency to form keloids;
malignant skin tumors prone to metastasis;
pregnancy;
age under 18 years;
lactation period;
hypersensitivity to the components of the drug.

Side Effects

The use of Mardil Selenium can lead to changes in skin pigmentation and the formation of superficial scarring.

With the normal course of the epithelization process, the absence of secondary infection and the spontaneous separation of mummified scabs, the likelihood of such consequences is low.

Swelling of the tissue may be observed; very rarely, with individual sensitivity to the components of the drug, allergic reactions in the form of skin itching are possible.

Interaction

The interaction of the drug Mardil Selenium with other external medications has not been established.

Overdose

If Mardil Selen is used incorrectly, in order to prevent damage to the deeper layers of the skin, the drug must be washed off with running water.

Healing can occur on its own without the use of additional medications or with the use of wound healing drugs.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C

Shelf life

2 years

Manufacturer

PharmVilar NPO LLC, Russia