Maltofer Fol, 30 pcs.

Maltofer® Fol contains iron in the form of a polymaltose complex of iron (III) hydroxide. This macromolecular complex is stable and does not release iron in the form of free ions in the gastrointestinal tract.

The structure of Maltofer® Fol is similar to the natural iron compound ferritin. Due to this similarity, iron (III) is transported from the intestine into the blood by active transport. It is this property that explains the impossibility of overdose of the drug in contrast to simple iron salts, the absorption of which occurs by a concentration gradient.

The absorbed iron is bound to ferritin and stored in the body, mainly in the liver. It is then incorporated into hemoglobin in the bone marrow. Iron, which is part of the polymaltose complex of iron (III) hydroxide, does not have pro-oxidant properties, unlike simple iron salts.

There is a correlation between the severity of iron deficiency and the level of iron absorption (the greater the severity of iron deficiency, the better the absorption). The most active absorption process occurs in the duodenum and small intestine.

Folic acid, a B vitamin, stimulates erythropoiesis and is involved in the synthesis of amino acids, nucleic acids, purines, pyrimidines and choline metabolism.

Maltofer® Fol in a dosage form of chewable tablets does not cause staining of teeth enamel.

Indications

Treatment of latent and clinically pronounced iron deficiency (iron deficiency anemia); prevention of iron and folic acid deficiency (including before, during and after pregnancy, during lactation).

Pharmacological effect

The drug Maltofer® Fol contains iron in the form of a polymaltose complex of iron (III) hydroxide. This macromolecular complex is stable and does not release iron in the form of free ions in the gastrointestinal tract.

The structure of Maltofer® Fol is similar to the natural iron compound ferritin. Due to this similarity, iron (III) moves from the intestine into the blood through active transport. It is this property that explains the impossibility of overdosing the drug, unlike simple iron salts, the absorption of which occurs along a concentration gradient.

Absorbed iron binds to ferritin and is stored in the body, mainly in the liver. It is then incorporated into hemoglobin in the bone marrow. Iron, which is part of the polymaltose complex of iron (III) hydroxide, does not have pro-oxidant properties, unlike simple iron salts.

There is a correlation between the severity of iron deficiency and the level of its absorption (the greater the severity of iron deficiency, the better the absorption). The most active absorption process occurs in the duodenum and small intestine.

Folic acid – a B vitamin – stimulates erythropoiesis, participates in the synthesis of amino acids, nucleic acids, purines, pyrimidines, and choline metabolism.

Maltofer® Fol in the dosage form of chewable tablets does not cause staining of tooth enamel.

Special instructions

One tablet of Maltofer® Fol contains 0.04 XE, which must be taken into account when prescribing to patients with diabetes.

Active ingredient

Iron III hydroxide polymaltosate, Folic acid

Composition

Active ingredients:

iron (III) hydroxide polymaltosate (equivalent to 100 mg iron); folic acid 0.35 mg;

Excipients:

dextrates;

macrogol 6000;

purified talc;

sodium cyclamate;

vanillin;

cocoa powder;

chocolate flavoring;

MCC;

Pregnancy

In controlled studies in pregnant women in the second and third trimesters of pregnancy, no undesirable effects of the drug on the mother and fetus were observed.

There is no data on the undesirable effect of the drug on the fetus during the first trimester of pregnancy.

Contraindications

iron overload (hemochromatosis, hemosiderosis);
impaired iron utilization (lead anemia, sideroachrestic anemia, thalassemia);
non-iron deficiency anemia (hemolytic anemia or megaloblastic anemia caused by vitamin B12 deficiency).

Side Effects

Very rare (≥0.001%,

Possible dark coloration of the stool due to the release of unabsorbed iron (no clinical significance).

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C.

Shelf life

5 years

Manufacturer

Vifor (International) Inc., Switzerland