Magnet B6, 50 pcs.

Magnesium is a vital element that is found in all body tissues and is necessary for the normal functioning of cells and is involved in most metabolic reactions. In particular, it is involved in the regulation of nerve impulse transmission and muscle contraction.

The body receives magnesium with food. Magnesium deficiency in the body may be observed in violation of the diet (diet) or increased need for magnesium (with increased physical and mental stress, pregnancy, use of diuretics). Pyridoxine (vitamin B6) is involved in many metabolic processes, in the regulation of nervous system metabolism. Vitamin B6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

The serum magnesium content:

• 12 to 17 mg/L (0.5 to 0.7 mmol/L) indicates moderate magnesium deficiency;
• below 12 mg/L (0.5 mmol/L) indicates severe magnesium deficiency.

Pharmacokinetics

Magnesium absorption in the gastrointestinal tract is no more than 50% of the oral dose. 99% of the body’s magnesium is intracellular. Approximately 2/3 of intracellular magnesium is distributed in bone tissue, and the other 1/3 is in smooth and striated muscle tissue. Magnesium is excreted mainly in the urine. With urine is excreted at least 1/3 of the dose of magnesium taken.

Indications

Active ingredient

Composition

Active substances:

magnesium lactate dihydrate – 470 mg;

pyridoxine hydrochloride – 5 mg;

Associates:

sucrose – 115.6 mg,

heavy kaolin – 40.0 mg,

acacia gum – 20.0 mg,

carboxypolymethylene 934 – 10.0 mg,

talc (magnesium disilicate) – 42.7 mg,

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magnesium stearate – 6.7 mg;

Pill coating:

Acacia gum – 3.615 mg, sucrose – 214.969 mg, titanium dioxide – 1.416 mg, talc (magnesium hydrosilicate) – traces, carnauba wax (powder) – traces;

How to take, the dosage

Adults are recommended to take 6-8 tablets per day.
Children over 6 years of age (body weight over 20 kg) 4-6 tablets per day.

Interaction

– Simultaneous use of drugs containing phosphates or calcium salts may significantly reduce magnesium absorption in the gastrointestinal tract. – Magnesium preparations reduce the absorption of tetracycline, it is recommended that an interval of 3 hours be taken before using Magnes B6. – Magnesium weakens the effect of oral thrombolytics, reduces the absorption of iron. – Vitamin B6 inhibits the activity of Levodopa.

Special Instructions

Information for patients with diabetes mellitus: coated tablets contain sucrose as an excipient. In case of concomitant calcium deficiency, magnesium deficiency should be eliminated before starting administration of additional calcium. With frequent use of laxatives, alcohol, strenuous physical and mental stress the need for magnesium increases, which may lead to magnesium deficiency in the body.

The ampoules contain sulfite which may cause or worsen allergic reactions, including anaphylactic reactions, in patients at risk. The drug in tablet dosage form is only for adults and children over 6 years of age. For younger children the drug in the dosage form of oral solution is recommended.

Influence on the ability to drive and other mechanisms

No effect.

Contraindications

With caution: in moderate renal failure because of the risk of hypermagnesemia.

Side effects

Allergic reactions, including skin reactions.

Overdose

Symptoms: With normal renal function, magnesium overdose when taken orally does not usually lead to toxic reactions. However, in cases of renal failure, magnesium poisoning may develop.

The symptoms of overdose, intensity of which depends on the concentration of magnesium in the blood: decrease of blood pressure; nausea, vomiting; depression of the central nervous system, decreased reflexes; changes on electrocardiogram; respiratory depression, coma, cardiac arrest and respiratory paralysis; anuric syndrome.

Treatment: rehydration, forced diuresis. In renal failure hemodialysis or peritoneal dialysis is necessary.

Pregnancy use

Pregnancy

The clinical experience of using the drug in a sufficient number of pregnant women has not revealed any adverse effect on the occurrence of fetal malformations or fetotoxic effects.
The drug Magne B6® can be used during pregnancy only if necessary, upon the doctor’s recommendation.

Breast-feeding period

Magnesium penetrates into the breast milk. The use of the drug during lactation and breastfeeding should be avoided.

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