Magnet B6, 10 ml 10 pcs

Magnesium is a vital element that is found in all body tissues and is necessary for the normal functioning of cells and is involved in most metabolic reactions. In particular, it is involved in the regulation of nerve impulse transmission and muscle contraction. The body gets magnesium with food.

Deficiency of magnesium in the body may be observed in violation of diet (diet) or increased demand for magnesium (with increased physical and mental stress, pregnancy, use of diuretics). Pyridoxine (vitamin B₆) is involved in many metabolic processes, in the regulation of metabolism of the nervous system. Vitamin B₆ improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

The serum magnesium content:

• 12 to 17 mg/L (0.5 to 0.7 mmol/L) indicates moderate magnesium deficiency;
• below 12 mg/L (0.5 mmol/L) indicates severe magnesium deficiency.

Pharmacokinetics

Magnesium absorption in the gastrointestinal tract is no more than 50% of the oral dose. 99% of magnesium in the body is inside the cells.

Approximately 2/3 of intracellular magnesium is distributed in bone tissue, and the other 1/3 is in smooth and transverse striated muscle tissue. Magnesium is excreted mainly in the urine. At least 1/3 of the administered dose of magnesium is excreted with urine.

Indications

Myalgia (muscle pain), Cramps, Neurosis, Insomnia, Cramps of the calf muscles, Weakness and fatigue, Magnesium deficiency, Tachycardia

• An established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as: Increased irritability, minor sleep disturbances;
• Gastrointestinal cramps or palpitations;
• Elevated fatigue, muscle aches and spasms, tingling sensation.

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Active ingredient

Magnesium, Pyridoxine

Composition

Active substances:

magnesium lactate dihydrate – 186 mg;

magnesium pidolate – 936 mg;

Pyridoxine hydrochloride – 10 mg;

Auxiliary substances:

Sodium disulfite – 15 mg,

Sodium saccharinate – 15 mg,

Cherry caramel flavoring – 0.3 ml,

purified water up to 10 ml;

How to take, the dosage

In adults it is recommended to take 3-4 ampoules per day.

In children older than 1 year of age (body weight over 10 kg) the daily dose is 10-30 mg of magnesium/kg of weight (0.4 – 1.2 mmol magnesium/kg) or 1-4 ampoules.

The daily dose should be divided into 2-3 doses, taken with meals.

The tablets should be washed down with a glass of water.

The solution from the ampoules is dissolved in a glass of water before taking.

The treatment should be stopped as soon as the concentration of magnesium in the blood is normalized.

Interaction

Magnesium weakens the effect of oral thrombolytics, reduces the absorption of iron. Vitamin B6 inhibits the activity of Levodopa.

Special Instructions

Pyridoxine, a component of Magne B6, significantly reduces the anti-Parkinsonian effect of levodopa.

Contraindications

• High sensitivity to the components of the drug.
• Developed renal failure (creatinine clearance less than 30 ml/minute).
• Phenylketonuria.
• Children under 6 years of age (for the drug in tablet form) and under 1 year (for the solution).
• Fructose intolerance, glucose-galactose malabsorption syndrome, sucrose-isomaltase deficiency (only for tablets due to sucrose content).
• Simultaneous use of levodopa.

With caution: in moderate renal failure because of the risk of hypermagnesemia.

Side effects

Allergic reactions, including skin reactions.

Overdose

Symptoms: With normal renal function, magnesium overdose when taken orally does not usually lead to toxic reactions. However, in cases of renal failure, magnesium poisoning may develop.

The symptoms of overdose, intensity of which depends on the concentration of magnesium in the blood: decreased blood pressure, nausea, vomiting, depression of the central nervous system, decreased reflexes, changes in the electrocardiogram, respiratory depression, coma, cardiac arrest and respiratory paralysis, anuric syndrome.

Treatment: rehydration, forced diuresis. In renal failure hemodialysis or peritoneal dialysis is necessary.

Pregnancy use

Pregnancy

The clinical experience of using the drug in a sufficient number of pregnant women has not revealed any adverse effect on the occurrence of fetal malformations or fetotoxic effects.
The drug Magnes B₆^® can be used during pregnancy only if necessary and on the doctor’s recommendation.

Lactation period

Magnesium penetrates into the breast milk. The use of the drug during lactation and breastfeeding should be avoided.

Similarities

Magnes B6 forte, Magnelis B6 forte, Magnelis B6