Magnesium sulfate, 250 mg/mL 10 ml 10 pcs

Tachycardia, Arrhythmia, Hypertension (high blood pressure)For parenteral administration: arterial hypertension (including hypertensive crisis with brain edema phenomena), threat of preterm birth, seizures in gestosis, hypomagnesemia (including increased magnesium requirement – tetany), myocardial dysfunction.including increased magnesium requirement and acute hypomagnesemia – tetany, myocardial dysfunction), polymorphic ventricular tachycardia (pirouette type), eclampsia, encephalopathy, epileptic syndrome, urinary retention.

Indications

For parenteral administration: arterial hypertension (including hypertensive crisis with symptoms of cerebral edema), threat of premature birth, convulsions during gestosis, hypomagnesemia (including increased need for magnesium and acute hypomagnesemia – tetany, impaired myocardial function), polymorphic ventricular tachycardia (pirouette type), eclampsia, encephalopathy, epileptic syndrome, urinary retention.

Special instructions

Take orally or administer parenterally with caution in case of heart block, myocardial damage, chronic renal failure, respiratory diseases, acute inflammatory diseases of the gastrointestinal tract, pregnancy.

Active ingredient

Magnesium sulfate

Composition

1 ml magnesium sulfate 250 mg
Excipients:
sodium hydroxide solution 1M – up to pH 5.5-8.0,
water for d/i – up to 1 ml.

Contraindications

Severe chronic renal failure, hypersensitivity to magnesium sulfate.
For oral administration: appendicitis, rectal bleeding (including undiagnosed), intestinal obstruction, dehydration.
For parenteral administration: arterial hypotension, depression of the respiratory center, severe bradycardia, AV block, prenatal period (2 hours before birth).
During pregnancy, magnesium sulfate is used with caution, only in cases where the expected therapeutic effect outweighs the potential risk to the fetus. If use is necessary during lactation, breastfeeding should be discontinued.
Contraindicated in severe chronic renal failure. Take orally or parenterally with caution in case of chronic renal failure.

Side Effects

Early signs and symptoms of hypermagnesemia: bradycardia, diplopia, sudden flushing of the face, headache, decreased blood pressure, nausea, shortness of breath, slurred speech, vomiting, weakness.

Interaction

With parenteral use of magnesium sulfate and simultaneous use of peripherally acting muscle relaxants, the effects of peripherally acting muscle relaxants are enhanced.

Overdose

Symptoms: Disappearance of the knee reflex, nausea, vomiting, sharp decrease in blood pressure, bradycardia, respiratory depression and central nervous system depression.

Clinical pharmacology

When administered parenterally, it has a hypotensive, sedative and anticonvulsant effect, as well as a diuretic, arteriodilatating, antiarrhythmic, vasodilating (on arteries) effect; in high doses, it has a curare-like effect (inhibitory effect on neuromuscular transmission), tocolytic, hypnotic and narcotic effects, suppresses the respiratory center.

Manufacturer

Grotex LLC, Russia