Magnesium sulfate, 250 mg/mL 10 ml 10 pcs

Tachycardia, Arrhythmia, Hypertension (high blood pressure)For parenteral administration: arterial hypertension (including hypertensive crisis with brain edema phenomena), threat of preterm birth, seizures in gestosis, hypomagnesemia (including increased magnesium requirement – tetany), myocardial dysfunction.including increased magnesium requirement and acute hypomagnesemia – tetany, myocardial dysfunction), polymorphic ventricular tachycardia (pirouette type), eclampsia, encephalopathy, epileptic syndrome, urinary retention.

Active ingredient

Magnesium sulfate

Composition

How to take, the dosage

Doses are specified taking into account the therapeutic effect and the content of magnesium ions in blood serum.

• Preeclampsia and eclampsia.saturation dose – 2-4 g in 5-20 min (infusion). The maintenance dose is 1-2 g per hour.
• Tetany of the uterus. The saturation dose is 4 g in 20 min (infusion). Maintenance dose – 1-2 g per hour at first, later 1 g per hour (can be administered by drip 24-72 h).
• Hypomagiaemia. In neonates. Daily dose is 0.2-0.8 ml/kg intravenously slowly. In adults. Mild. Magnesium sulfate solution is administered parenterally if it is not possible to take magnesium preparations orally (due to nausea, vomiting, impaired resorption in the stomach, etc.) the daily dose is 1-2 g. This dose should be given as a single dose or in 2-3 doses. Severe. Initial dose is 5 g, which is delivered in 1 liter of infusion solution and slowly administered intravenously. Dosed according to the concentration of the drug in the blood serum.
• Prevention of hypomagia in patients receiving parenteral nutrition only. If there is no magnesium in the nutrient solutions, it is added additionally. The daily dose is 1.5-4 g. Usually 1 g of magnesium sulfate is added to 1 liter of parenteral nutrition solution. The maximum daily dose of magnesium sulfate for adults is 40 g.
• In hypertensive crises, 5-20 ml of magnesium sulfate 250 mg/ml solution is given intravenously (slowly).
• To stop arrhythmias, 1 to 2 g intravenously for about 5 minutes, repeated administration is possible.

Doses of magnesium sulfate are given in grams. They correspond to the amount of 250 mg/ml solution: 1 g – 4 ml; 2 g – 8 ml; 3 g – 12 ml; 4 g – 16 ml; 5 g – 20 ml; 10 g – 40 ml; 15 g – 60 ml; 20 g – 80 ml; 30 g – 120 ml; 40 g – 160 ml.
Magnesium sulfate solution in ampoules is diluted with injection solutions: 0.9% sodium chloride or 5% dextrose (glucose).
Procedure of work with polymer ampoule:
1. Take the ampoule and shake it holding the neck.
2. Press the ampoule by hand, the preparation should not be released, and twisting movements turn and separate the valve.
3. Through the opening formed immediately connect the syringe to the ampoule.
4. Turn the ampoule over and slowly draw the contents into the syringe.
5. Put the needle on the syringe.

Interaction

Parenteral administration of magnesium sulfate and concomitant use of peripheral myorelaxants increases the effects of peripheral myorelaxants.

Special Instructions

Use with caution when administered orally or parenterally in cardiac blockade, myocardial damage, chronic renal failure, respiratory diseases, acute inflammatory gastrointestinal diseases, pregnancy.

Contraindications

Side effects

Early signs and symptoms of hypermagnesemia: bradycardia, diplopia, sudden rush of blood to the face, headache, decreased BP, nausea, shortness of breath, blurred speech, vomiting, weakness.

Overdose

Symptoms: Disappearance of knee reflex, nausea, vomiting, sharp decrease in blood pressure, bradycardia, depression of respiration and central nervous system.

Similarities

Magnesium sulfate, Magnesium sulfate