Magnerot, tablets 500 mg 20 pcs

Magnesium is a preparation of magnesium. Magnesium is a macronutrient required for many energy processes, is involved in the metabolism of proteins, fats, carbohydrates and nucleic acids.

Magnesium is involved in the process of neuromuscular excitation by inhibiting neuromuscular transmission. Magnesium is of particular interest as a natural physiological calcium antagonist. Magnesium controls the normal functioning of myocardial cells, is involved in the regulation of myocardial contractile function. In stressful situations, increased amounts of free ionized magnesium are excreted, so that additional amounts of magnesium contribute to resistance to stress.

Magnesium deficiency leads to neuromuscular disorders (motor and sensory hyperexcitability, seizures, paresthesia), mental changes (state of depression, confusion and hallucinations), cardiovascular disorders (ventricular extrasystoles, tachycardia, hypersensitivity to cardiac glycosides). Magnesium deficiency during pregnancy increases the likelihood of toxicosis and premature birth. Salts of orotic acid are involved in the metabolic process. In addition, orotic acid salts are necessary for magnesium fixation to ATP in the cell and its manifestation.

Pharmacokinetics

The absorption is approximately 35-40% of the dose taken. Hypomagnesemia stimulates absorption of magnesium ions. The presence of orotic acid salts promotes magnesium absorption. Magnesium is excreted by the kidneys, the excretion decreases in magnesium deficiency and increases in magnesium excess.

Indications

Active ingredient

Composition

Active ingredient:

Magnesium orotate dihydrate 500 mg;

Auxiliary substances:

colloidal silicon dioxide, 2.5 mg;

sodium carmellose, 10 mg;

MCC – 67.5 mg;

Corn starch – 22.5 mg;

p> povidone K30 – 30 mg;

lactose monohydrate – 50 mg;

sodium cyclamate – 1.5 mg;

talc, 18.75 mg;

magnesium stearate, 1.63 mg;

How to take, the dosage

Overly, before meals, with a small amount of liquid.

Prescribe 2 tablets 3 times a day for 7 days, then 1 tablet 2-3 times a day daily.

The course duration is at least 4-6 weeks. If necessary Magnerot® can be used for a long time.

In case of nocturnal cramps of the calf muscles, it is recommended to take 2-3 tablets in the evening.

Interaction

Special Instructions

Magnerot® can be used for a long time.

. It should be taken into account that diseases of gastrointestinal tract, consumption of food with low magnesium content, sports activities (due to increased sweating), and chronic alcoholism (due to decrease of magnesium resorption in renal tubules and increased magnesium ions excretion) may lead to magnesium deficiency in the body, intake of certain drugs (cardiac glycosides, aminoglycoside antibiotics, oral contraceptives, diuretics, laxatives, GCS), conditions requiring increased magnesium intake (hypodynamia, stress, pregnancy and lactation), prolonged exposure to the sun.

Impact on the ability to drive a car or perform work requiring increased speed of physical and mental reactions. The drug does not affect the ability to drive vehicles and other activities requiring high concentration and speed of psychomotor reactions.

Synopsis

Features

Contraindications

Side effects

Overdose

Pregnancy use

The drug can be used during pregnancy and lactation (breast-feeding) on indication, because during these periods the need for magnesium increases significantly.

If its content is not balanced, it may lead to serious complications, including pregnancy failure.

The use of the drug during pregnancy and lactation is possible if the potential benefit to the mother exceeds the potential risk to the fetus and child.

Similarities