Lidocaine, 100 mg/ml 2 ml 10 pcs

Indications

– local infiltration anesthesia;

Active ingredient

How to take, the dosage

The amount of lidocaine solution and the total dose depends on the type of anesthesia, the nature and duration of the surgical intervention.

The method of diluting 20 mg/ml (2%) lidocaine solution to obtain the desired solution concentration:

To prepare 10 mg/mL (1%) lidocaine solution, take 1 part 20 mg/mL lidocaine solution and 1 part water for injection, that is, mix 2 mL 20 mg/mL lidocaine solution with 2 mL water for injection (for a 2-mL ampoule), or mix 5 mL 20 mg/mL lidocaine solution with 5 mL water for injection (for a 5-mL ampoule).

To prepare 5 mg/ml (0.5%) lidocaine solution, use 1 part 20 mg/ml lidocaine solution and 3 parts water for injection, i.e. mix 2 ml 20 mg/ml lidocaine solution with 6 ml water for injection (for 2 ml ampoule), or mix 5 ml 20 mg/ml lidocaine solution with 15 ml water for injection (for 5 ml ampoule).

To prepare 2.5 mg/ml (0.25%) lidocaine solution, take 1 part 20 mg/ml lidocaine solution and 7 parts water for injection, i.e. Mix 2 ml of 20 mg/ml lidocaine solution with 14 ml of water of injection (for 2 ml ampoule), or mix 5 ml of 20 mg/ml lidocaine solution with 35 ml of water of injection (for 5 ml ampoule).

To prepare 1.25 mg/ml (0.125%) lidocaine solution, take 1 part 20 mg/ml lidocaine solution and 15 parts water for injection, i.e. Mix 2 ml of 20 mg/ml lidocaine solution with 30 ml of water of injection (for 2 ml ampoule), or mix 5 ml of 20 mg/ml lidocaine solution with 75 ml of water of injection (for 5 ml ampoule).

For infiltration anesthesia (intradermal, subcutaneous) 0.125%, 0.25%, 0.5% solutions are used; to achieve infiltration anesthesia up to 60 ml (5-300 mg) of 0.5% solution or up to 30 ml of 1% solution is used.

For peripheral nerve conduction anesthesia (anesthesia of peripheral nerves including plexus blockade) 1% and 2% solutions are used; the maximum total dose is up to 400 mg (40 ml of 1% solution or 20 ml of 2% solution). For plexus blockade 10-20 ml of 1% solution or 5-10 ml of 2% solution.

For peripheral nerve conduction anesthesia: brachial – 15-20 ml (225-300 mg) 1.5% solution; in dental practice – 1-5 ml (20-100 mg) 2% solution; intercostal nerve blockade – 3 ml (30 mg) 1% solution.

For paracervical anesthesia: 10 ml (100 mg) of 1% solution in each side, if necessary, it is possible to reintroduce at least 1.5 hours later.

For paravertebral anaesthesia: 3 to 5 ml (30-50 mg) of 1% solution. Retrobulbar anesthesia: 3.0 to 4.0 (60-80 mg) 2% solution.

Parabulbar anesthesia – 1.0-2.0 (20-40 mg) 2% solution. Vagosympathetic blockade: cervical (stellate node) – 5 ml (50 mg) of 1% solution, lumbar – 5-10 ml (50-100 mg) of 1% solution.

Spinal anesthesia – 3.0-4.0 ml (60-80 mg) of 2% solution.

Epidural anesthesia – 25-30 ml (250-300 mg) of 1% solution is used to obtain analgesia; 15-20 ml (225-300 mg) of 1.5% solution or 10-15 ml (200-300 mg) of 2% solution to obtain anesthesia; 20-30 ml (200-300 mg) of 1% solution is used for thoracic epidural anesthesia. Continuous administration of the anesthetic with a catheter is not recommended; the maximum dose should not be repeated more often than 90 minutes.

When using caudal anesthesia: in surgical practice, 15-20 ml (225-300 mg) of 1.5% solution. Continuous administration of the anesthetic with a catheter is not recommended; the maximum dose should not be repeated more often than 90 min later. Recommended doses in children for neuromuscular blockade are up to 4.5 mg/ml 0.25-1.0% solution.

The maximum dose for children is 4.5 mg/kg, but no more than 100 mg; the maximum dose for adults is no more than 4.5 mg/kg or 300 mg. These doses must be repeated within 24 hours.

The effect of lidocaine may be prolonged by adding 0.1% epinephrine solution (0.1 ml per 20 ml lidocaine). In this case, in regional anesthesia the dose of lidocaine may be increased to 600 mg.

Polymer ampoule procedure:

1.Take the ampoule and shake it, holding it by the neck.

2.Squeeze the ampoule with your hand, taking care not to release the product, and with a twisting motion, turn and separate the valve.

3.Through the hole that is created, immediately connect the syringe to the ampoule.

4. Turn the ampoule over and slowly draw the contents into the syringe.

5. Slide the needle onto the syringe.

Interaction

Special Instructions

Contraindications

Side effects

The frequency of side effects is given in accordance with the classification of the World Health Organization: very common – at least 10%; common – at least 1% and less than 10%; rare – at least 0.01% and less than 0.1%; very rare – less than 0.01%, including isolated cases.

From the central nervous system and sensory organs: frequent – dizziness, headache, weakness, infrequent – motor restlessness, rare – nystagmus, loss of consciousness, drowsiness, visual and auditory disturbances, tremor, trism, seizures (the risk of their development increases against a background of hypercapnia and acidosis), very rare – paralysis of respiratory muscles, respiratory arrest, motor and sensory block, respiratory paralysis (develops more often in subarachnoid anesthesia).

The cardiovascular system: often – increase or decrease of blood pressure, rarely – bradycardia, arrhythmia, tachycardia – when administered with a vasoconstrictor, very rarely – peripheral vasodilation, collapse, pain in the chest.

Gastrointestinal tract: frequently – nausea, vomiting, involuntary defecation.

Blood: infrequent – methemoglobinemia.

Local reactions: often – in spinal anesthesia – back pain, in epidural anesthesia – accidental penetration into the subarachnoid space.

Allergic reactions: often – skin rash, urticaria (on the skin and mucous membranes), skin itching, very rarely – angioedema, anaphylactic shock.

Others: infrequent – persistent anesthesia, very rare – respiratory depression, up to and including respiratory arrest, hypothermia.

Overdose

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