Levocetirizine-Teva, 5 mg 14 pcs.

Levocetirizine is the active substance of the drug Levocetirizine-Teva is the R-enantiomer of cetirizine, which belongs to the group of competitive histamine antagonists and blocks H1-histamine receptors.

Levocetirizine influences the histamine-dependent stage of allergic reactions and also reduces migration of eosinophils, decreases vascular permeability and limits release of inflammatory mediators.

Levocetirizine prevents development and facilitates allergic reactions, has antiexudative and antipruritic action and practically has no anticholinergic and antiserotonic action.

In therapeutic doses it has practically no sedative effect.

Indications

Active ingredient

How to take, the dosage

Interaction

Theophylline (400 mg/day) decreases total clearance of levocetirizine by 16%, while the kinetics of theophylline is not changed.

Co-administration with macrolides or ketoconazole did not cause significant changes in ECG.

Special Instructions

During treatment, it is necessary to refrain from potentially hazardous activities that require high concentration and rapid psychomotor reactions, as well as from drinking ethanol.

Contraindications

Hypersensitivity (including to piperazine derivatives), severe CKD (IQ less than 10 ml/min), pregnancy, lactation, children (under 6 years).

With caution. CKD, advanced age (decreased glomerular filtration is possible).

Side effects

Headache, drowsiness, dry mouth, fatigue, rarely – migraine, dizziness, dyspepsia, allergic reactions (angioedema, rash, urticaria, skin itching).

Overdose

Symptoms: drowsiness, in children – anxiety, irritability.

Treatment: gastric lavage, activated charcoal, symptomatic therapy. There is no specific antidote. Hemodialysis is not effective.

Similarities