Laxigal, drops 7.5 mg/ml 25 ml

Laxigal is a laxative.

The active form of the drug formed by hydrolysis under the influence of intestinal microorganisms directly excites the nervous structures of the intestinal wall, resulting in accelerated progression of intestinal contents, reduced absorption of electrolytes and water.

The action occurs 10-12 hours after intake.

Pharmacokinetics

After oral administration is not absorbed from the GI tract and is not subject to hepatic-intestinal circulation.

Indications

• iatonic constipation
• stool regulation (hemorrhoids, proctitis, cracks anus)
• preparing for surgical procedures, instrumental and radiological studies.
  

Active ingredient

Sodium picosulfate

Composition

Active substance:

Sodium picosulfate monohydrate (in terms of 100% substance) 7.5 mg;

Auxiliary substances:

sorbitol liquid 70% uncrystallized – 680 mg;

ethyl parahydroxybenzoate sodium – 0.66 mg;

Hydrochloric acid 35% – up to the required amount;

water up to – 1 ml

How to take, the dosage

Ingestion, before bedtime, diluted in a small amount of water.

Adults and children over 10 years of age take 12-24 drops (5-10 mg).

Children from 4 to 10 years – 6-12 drops (2.5-5 mg).

Depending on the effect, the dose is increased or decreased in subsequent doses.

Interaction

An increased sensitivity to cardiac glycosides is possible.

GCS, diuretics increase the risk of electrolyte disturbances.

The broad-spectrum antibiotics decrease the laxative effect.

Contraindications

• intestinal obstruction;
• pinched hernia;
• acute inflammatory diseases of the abdominal cavity;
• peritonitis;
• abdominal pain (of unclear genesis)
• gastrointestinal bleeding;
• metrorrhagia;
• cystitis;
• severe dehydration;
• spastic constipationspastic constipation;
• children (under 4 years);
• pregnancy (first trimester);
• hypersensitivity.

With caution: period of lactation.

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Side effects

Possible: diarrhea, abdominal pain, dehydration, disorders of water-electrolyte balance, weakness, seizures, decreased blood pressure.

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Overdose

Symptoms: in chronic overdose development of colonic mucosal ischemia, secondary hyperaldosteronism, urolithiasis, renal tubule damage is possible.

Treatment: gastric lavage, correction of disorders of water-electrolyte balance, antispasmodic agents.

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Similarities

Regulax Picosulfate, Guttalax, Slabilen, Slabicap, Picodinar