Laifevit, capsules 100 mg 30 pcs

Indications

Prevention and treatment of vitamin E hypovitaminosis, including:

• Degenerative and proliferative changes in the musculoskeletal system, in particular muscular dystrophy, amyotrophic lateral sclerosis (as part of complex therapy);
• Cronic hepatitis (as part of complex therapy);
• States of recuperation after severe diseases, injuries, operations
• Tough physical activity
• Menstrual disorders (as part of the treatment of hormonal treatment of menstrual disorders).

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Composition

• Alpha-tocopherol acetate – 100 mg
• Associates:
• sunflower oil – 7.5 mg
• Capsule shell:
• gelatin – 49.38 mg;
• glycerol 85% – 27.46 mg;
• methyl parahydroxybenzoate – 0.049 mg;
• punsenol dye Ponceau 4R (E124) – 0.22 mg;
• purified water – 32.898 mg

Interaction

Enhances the effect of GCS, NSAIDs, cardiac glycosides.

It increases the effectiveness of antiepileptic drugs in patients with epilepsy (who have increased levels of lipid peroxidation products in the blood).

High doses of iron increase oxidative processes in the body, which increases the need for vitamin E.

The simultaneous use of vitamin E in a dose greater than 400 ME/d with anticoagulants (coumarin and indandion derivatives) increases the risk of hypoprothrombinemia and bleeding.

Vitamin E increases the effect of anticoagulants if doses exceed 400 ME/day.

The simultaneous use of other vitamin complexes containing vitamin E is not recommended to avoid overdose.

Prescribing vitamin E in high doses may cause vitamin A deficiency in the body. Colestiramine, colestipol, and mineral oils reduce vitamin E absorption.

Directions for use

Ingestion. The drug is intended to be taken only by adult patients.

Treatment of vitamin E hypovitaminosis – 100 mg capsules once a day until the symptoms of hypovitaminosis disappear.

Hypovitaminosis of vitamin E accompanied with degenerative and proliferative changes in the musculoskeletal system, in particular muscular dystrophy, amyotrophic lateral sclerosis (in combination therapy) – 100 mg capsules 1 time daily for 1-2 months.

Hypovitaminosis E with chronic hepatitis (in complex therapy) – 100 mg capsules once a day.

Hypovitaminosis E in conditions of convalescence after severe diseases and injuries and surgeries – 100 mg capsules once a day for 1 to 2 weeks.

Hypovitaminosis E with increased physical activity – 100 mg capsules once a day during periods of intense physical activity.

Hypovitaminosis E with menstrual disorders (as part of complex therapy in the hormonal treatment of menstrual disorders) – 300-400 mg cap. every day sequentially, starting from the 17th day of the cycle till the last day of the cycle (the day before the first day of menstruation).

Special Instructions

In congenital bullous epidermolysis, white hair may begin to grow in areas affected by alopecia.

Deficiency of vitamin K in the body, causing hypoprothrombinemia, may be increased with high doses of vitamin E (over 400 IU/day). Vitamin E increases the effect of anticoagulants if doses exceed 400 ME/day. In order to avoid overdose, it is not recommended to take other vitamin complexes containing vitamin E at the same time.

Impact on the ability to drive vehicles or mechanisms. Administration of Vitamin E Zentiva, Capsules does not affect the person’s ability to drive vehicles or operate machinery.

Contraindications

• High sensitivity to the drug components;
• Acute myocardial infarction;
• Children.

With caution: In patients with severe cardiosclerosis, myocardial infarction, increased risk of thromboembolism; hypothrombinemia caused by vitamin K deficiency may worsen when vitamin E is used at a dose greater than 400 ME (1 mg – 1.21 ME).

Overdose

Symptoms: high doses of vitamin E (400-800 mg/day for a long time) can cause visual disturbances, diarrhea, dizziness, headache, nausea, severe fatigue, fainting, white hair growth on areas of alopecia in bullous epidermolysis.

Very high doses (exceeding 800 mg for a long time) may cause bleeding in patients with vitamin K deficiency; they may disrupt thyroid hormone metabolism and increase the risk of thrombophlebitis and thromboembolism in sensitive patients.

Treatment: symptomatic, drug withdrawal, prescription of GCS.