Ketoconazole, vaginal suppositories 400 mg 5 pcs
€11.14 €9.75
Antifungal agent.
It has fungicidal and fungistatic action.
The mechanism of action is inhibition of ergosterol synthesis and changes in the lipid composition of the membrane.
It is active against the causative agent of variegated lichen Malassezia furfur, causative agents of some dermatomycoses (Trichophyton, Epidermophyton floccosum, Microsporum), causative agents of candidiasis (Candida) as well as causative agents of systemic mycoses (Cryptococcus).
It is also active against Gram-positive cocci: Staphylococcus spp., Streptococcus spp.
Indications
Fungal infections of the gastrointestinal tract, genital organs, skin, hair (including seborrheic dermatitis), nails, caused by sensitive pathogens. Systemic mycoses. Prevention of fungal lesions in patients with an increased risk of their development.
Active ingredient
Composition
Active ingredient:
ketoconazole 400 mg
How to take, the dosage
Intravaginally.
Pre-release the suppository from the contour pack and insert it deep into the vagina in the supine position for 1 suppository per day for 3-5 days depending on the course of the disease.
In chronic candidiasis 1 suppository is used for 10 days.
If after treatment there is no improvement or new symptoms appear, it is necessary to consult a doctor.
Interaction
Ketoconazole is practically not subject to systemic absorption when used intravaginally as a suppository and interactions with other drugs are unlikely.
Special Instructions
In rare cases, allergic reactions (penile hyperemia) in the sexual partner may occur.
To reduce the risk of recurrence of the disease, concomitant treatment of the sexual partner is recommended.
The use of suppositories may reduce the reliability of mechanical contraception (latex-containing condoms and vaginal diaphragms).
Impact on the ability to drive vehicles and operate potentially dangerous machinery
The use of the drug does not affect the ability to drive vehicles and operate potentially dangerous machinery.
Contraindications
Expressed liver and kidney function abnormalities, pregnancy, lactation, hypersensitivity to ketoconazole.
Side effects
Digestive system disorders: in rare cases – nausea, vomiting, diarrhea.
CNS and peripheral nervous system disorders: in rare cases – headache, dizziness, sleep disorders, paresthesias.
Dermatological reactions: in rare cases exanthema; very rare – hair loss.
As to the sexual system: very rare – gynecomastia, decreased libido, oligospermia.
Allergic reactions: very rare – urticaria, skin rash.
Other: in rare cases – photophobia, thrombocytopenia; very rare – arthralgia, fever.
Overdose
Because of the low absorption of the drug when used in the recommended (therapeutic) doses, there can be no overdose.
Overdose with intravaginal use is unlikely.
Similarities
Weight | 0.020 kg |
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Shelf life | 3 years |
Conditions of storage | In a light-protected place at 15-25 °C |
Manufacturer | Avexima Siberia, Russia |
Medication form | vaginal suppositories |
Brand | Avexima Siberia |
Other forms…
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