Nizoral, medicated shampoo 2% 120 ml

Pharmacodynamics

Ketoconazole, a synthetic imidazole-dioxolane derivative, has antifungal action against dermatophytes such as Trichophyton sp, Epider-mophyton sp., Microsporum sp., and yeasts such as Candida sp. and Malassezia furfur (Pityrosporum ovale).

Ketoconazole shampoo quickly reduces the flaking and itching usually associated with dandruff, seborrheic eczema and pityriasis.

Pharmacokinetics

Ketoconazole absorption through the skin when used topically is negligible.

Since even with long-term use ketoconazole content in blood is not determined, we can conclude that the drug has no systemic action.

Indications

Treatment and prevention of skin lesions caused by the yeast-like microorganisms Malassezia furfur (Pityrosporum ovale), such as dandruff and peptic ulcer (localized).

Active ingredient

Ketoconazole

Composition

Active ingredient:

Ketoconazole, 21 mg/g (5% excess).

Auxiliary Substances:

Macrogol methyldextrose dioleate,

Imidourea,

Cocoyl diethanolamide,

Collagen hydrolyzate,

Sodium hydroxide,

Sodium lauryl sulfate,

Sodium sulfate,

Sodium lauryl sulfosuccinate,

Sodium chloride,

Hydrochloric acid,

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Flavoring,

Red Charming Dye (E 129),

Water.

How to take, the dosage

Apply Nizoral 2% shampoo to the affected areas for 3-5 minutes, then rinse with water.

Treatment:

• Dandruff and seborrheic eczema: twice a week for 3-4 weeks.
• Hodgepodge: daily for 5 days.

Prevention:

• Dandruff and seborrheic eczema: weekly or once every two weeks.
• Rubella: daily for 3 days (one-time treatment) before summer.

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Special Instructions

When using shampoo, avoid getting it in the eyes. If shampoo gets into the eyes, rinse with water.

In order to prevent withdrawal syndrome with prolonged topical corticosteroid treatment, continued topical use of corticosteroids in combination with Nizoral 2% Shampoo is recommended, followed by gradual withdrawal of corticosteroids over 2-3 weeks.

Seborrheic dermatitis and dandruff are often accompanied by increased hair loss. In rare cases, increased hair loss has been noted when using Nizoral 2% shampoo.

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Contraindications

High sensitivity to any of the ingredients of the shampoo.

Side effects

Nizoral 2% Shampoo is generally well tolerated.

As with other shampoos, there may be local irritation, itching or contact dermatitis (due to irritation or allergic reaction) Hair may become greasy or dry.

However, these phenomena are rare with Nisoral 2% shampoo.

In isolated cases, mainly in patients with chemically damaged or gray hair, changes in hair color have been noted.

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Similarities

Nisoral, Mycosoral, Livarol, Perchotal, Ketoconazole Shampoo, Ketoconazole DS, Ketoconazole