Iodine 5% leekker-floumer, 5 ml

Elemental iodine has pronounced antimicrobial properties. Elemental iodine preparations are characterized by a pronounced local irritating effect on tissues, and in high concentrations – a cauterizing effect. Local action is due to the ability of elemental iodine to precipitate tissue proteins. Preparations that detach elemental iodine have much less pronounced irritating effect, and iodides have local irritating properties only in very high concentrations.

The nature of the resorptive action of preparations of elemental iodine and iodides is the same. Iodine preparations have the most pronounced resorptive effect on thyroid function. In case of iodine deficiency, iodides help to restore the disturbed synthesis of thyroid hormones. At normal levels of iodine in the environment, iodides inhibit the synthesis of thyroid hormones, reducing the sensitivity of the thyroid gland to pituitary TSH and blocking its secretion by the pituitary gland. The effect of iodine preparations on metabolism is manifested by increased dissimilation. At atherosclerosis they cause some decrease in concentration of cholesterol and beta-lipoproteides in blood; besides they increase fibrinolytic and lipoproteinase activity of blood serum and slow down the rate of blood coagulation.

The accumulation of iodine in syphilitic gummas promotes their softening and resorption. However, iodine accumulation in tubercular foci leads to an intensification of the inflammatory process in them. Iodine release by excretory glands is accompanied by irritation of glandular tissue and increased secretion. This causes expectorant action and stimulation of lactation (in small doses). However, in high doses iodine preparations may cause suppression of lactation.

Pharmacokinetics

On contact with skin or mucous membranes 30% is converted to iodides and the rest to active iodine. It is partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is excreted mainly by the kidneys, intestines, sweat and mammary glands.

Indications

For external use: infectious-inflammatory skin lesions, injuries, wounds, myalgias.

For local use: chronic tonsillitis, atrophic rhinitis, purulent otitis, trophic and varicose ulcers, wounds, infected burns, fresh thermal and chemical burns of I-II degree.

Composition

Active substance: iodine

How to take, the dosage

Externally, on the damaged areas of the field.

Interaction

Pharmaceutically incompatible with essential oils, ammonia solutions, white sediment mercury (an explosive mixture is formed). Alkaline or acidic environment, presence of fat, pus, blood weaken antiseptic activity. It weakens hypothyroid and strumogenic effects of lithium preparations.

Special Instructions

Iodism phenomena are possible with prolonged use.

Contraindications

Hypersensitivity to iodine. For oral use – pulmonary tuberculosis, nephritis, nephrosis, adenomas (including thyroid), furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, urticaria, pregnancy, children under 5 years.

Side effects

In external use: seldom – skin irritation; with prolonged use on extensive wound surfaces – iodism (rhinitis, urticaria, Quincke’s edema, salivation, lacrimation, acne).