Iodine, alcohol 5% 25 ml

An antiseptic agent. The main active ingredient is molecular iodine, which has antiseptic properties. When applied to extensive skin surfaces, iodine has a resorptive effect: it actively affects metabolism, participates in the synthesis of thyroxine, has a proteolytic effect. Ethyl alcohol is a high molecular weight compound which slows down iodine excretion and reduces its irritating effect on tissues.

It has a bactericidal effect, both on Gram-positive flora (most active on Streptococcus and Escherichia coli) and on pathogenic fungi and yeast. Staphylococcus aureus is more persistent flora, but it disappears with long-term use of the drug in 80% of cases. Pseudomonas bacillus is resistant. The drug is little toxic.

Pharmacokinetics

On contact with the skin 30% is converted to iodides, and the remainder penetrates tissues and organs, selectively absorbed by the thyroid gland. It is excreted by the kidneys (mainly), intestines, sweat glands, with milk during lactation.

Indications

Inflammatory and infectious skin diseases, abrasions, cuts, microtraumas, wounds; myositis, neuralgia, inflammatory infiltrates; disinfection of the operating field (pre- and postoperative treatment of the operating field, injections, punctures, catheterization), the edges of wounds, surgeon’s hands.

Composition

Active ingredients: iodine – 5%;

Auxiliary substances: potassium iodide, ethanol, purified water.

Interaction

Pharmaceutically incompatible with essential oils, ammonia solutions, white sedimentary mercury (forms an explosive mixture).

Directions for use

Externally, the affected areas of the skin are smeared. When treating the operating field the skin is wiped twice with a sterile gauze tampon soaked in the solution. Total treatment time is 4-6 minutes.

Special Instructions

When used together with yellow mercury ointment, mercury iodide may form, which has a cauterizing effect.

Synopsis

Antiseptic preparation for external use. It has a fast bactericidal effect (within 15-60 seconds), anti-inflammatory, distracting and resolving action. It is effective for inflammatory and infectious skin diseases, small skin lesions, inflammatory infiltrates; for treatment of wound edges, skin before injections, punctures, catheterization; for myositis and neuralgia – as a distraction agent.

Contraindications

Hypersensitivity.

Side effects

Skin irritation, with prolonged use on extensive wound surfaces – iodism (rhinitis, urticaria, Quincke’s edema, salivation, lacrimation, acne).