Ibuprofen-Acrihin, 100 mg/5 ml orange 100 ml suspension

Non-steroidal anti-inflammatory drug, a derivative of phenylpropionic acid.

It has anti-inflammatory, analgesic and antipyretic effects. The drug effect is due to inhibition of prostaglandin synthesis by blocking the enzyme cyclooxygenase.

Inhibits platelet aggregation. With prolonged use it has a desensitizing effect.

Indications

• rheumatoid arthritis;
• osteoarthritis;
• ankylosing spondylitisAnkylosing spondylitis;
• podagra;
• neuralgia;
myalgia;
• burritis;
• radiculitis;
• traumatic inflammation of the soft tissue and musculoskeletal system;
• adnexitis (in the treatment);
• proctitis (in the treatment);
• diseases of ENT-organs (in the treatment);
• headache (as an adjuvant);
• dental pain (as an adjuvant).

Active ingredient

Ibuprofen

Composition

Composition of 100 ml of suspension:

active ingredient:
ibuprofen – 2 g;

auxiliary components:

sodium phosphate dihydrate – 0.46 g;
propylene glycol – 1.71 g;
propyl parahydroxybenzoate – 0.05 g;
Citric acid monohydrate – 0,91 g;
crosspovidone – 0,14 g;
sodium saccharinate – 0,25 g;
glycerol – 5,7 g;
sodium carmellose – 0,97 g;
methylparahydroxybenzoate – 0,57 g;
sodium trichloride – 6,8 g;
ammonium sulfate – 6,8 g. Methyl parahydroxybenzoate – 0,15 g;
Macrogoal glycerylhydroxystearate – 1,14 g;
sucrose – 34,2 g;
Magnesium-aluminium silicate (Veegum) – 0,57 g;
sunset yellow dye (E110) – 0,02 g;
orange flavoring – 0,34 g;
purified water – up to 100 ml.

How to take, the dosage

In rheumatoid arthritis 800 mg 3 times a day is prescribed.

In osteoarthritis and ankylosing spondylitis Ibuprofen is used in 400-600 mg 3-4 times a day.

In juvenile rheumatoid arthritis the drug is used in a dose of 30-40 mg/kg body weight per day.

In case of trauma of soft tissues, sprain of ligaments the drug is prescribed in dose of 600 mg 2-3 times a day.

In moderate-intensity pain syndrome the drug is prescribed in 400 mg 3 times a day. Maximal daily dose is 2.4 g.

Interaction

In concomitant administration Ibuprofen may decrease the diuretic effect of furosemide.

When co-administration Ibuprofen increases the effect of diphenin, coumarin anticoagulants, oral hypoglycemic agents.

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Special Instructions

The drug is prescribed with caution in patients with impaired liver function, renal function, cardiovascular system diseases, with a history of peptic ulcer and/or duodenal ulcer, gastrointestinal bleeding.

Compared with other NSAIDs, Ibuprofen has the least ulcerogenic effect on the gastrointestinal mucosa.

When using the drug for a long time it is necessary to monitor the liver and/or kidney function and peripheral blood picture.
During pregnancy the drug should be used only if prescribed by the doctor.

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Contraindications

• gastrointestinal erosive and ulcerative lesions in the stage. exacerbations;
• “aspirin” triad;
• blood disorders;
• ulcerative colitis;
• optic nerve disease;
• explicit renal and/or hepatic dysfunction;
• children under 6 years of age;
• high sensitivity to the drug.

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Side effects

Possible: nausea, anorexia, flatulence, constipation, heartburn, diarrhea, dizziness, headache, agitation, insomnia, allergic reactions in the form of skin rash, visual disturbances.

There have been cases of gastrointestinal erosive and ulcerative lesions.

Rarely: bleeding from the gastrointestinal tract, aseptic meningitis, bronchospasm.

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Similarities

Nurofen, Nurofen Express, Brufen, Ibuprofen, Dolgit, Ibuprofen-Chemopharm, Nurofen Forte, MIG 400, Faspik, Nurofen Express Lady, Nurofen Express Forte, Nurofen Children, Next Uno Express, Nurofast