Ibuklin, 400 mg+325 mg 10 pcs

Joint pain (arthralgia), Painful menstruation (algodysmenorrhea), Fever, Toothache, Myalgia (muscle pain), Headache, Bruises, Neuralgia, Acute respiratory infections

• .Symptomatic therapy of infectious and inflammatory diseases (colds, flu) accompanied by fever, chills, headache, pain in muscles and joints, sore throat;
• .Myalgia,
• neuralgia,
• backache,
• joint pain, pain syndrome of inflammatory and degenerative diseases of the musculoskeletal system
• pain

pain at bruises, sprains, dislocations, fractures;

• post-traumatic and postoperative pain syndrome;
• dental pain;
• aldysmenorrhea (painful menstruation).

The drug is intended for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease.

Active ingredient

How to take, the dosage

Interaction

In concomitant use with acetylsalicylic acid ibuprofen reduces its anti-inflammatory and antiaggregative effects (increased incidence of acute coronary failure in patients receiving low-dose acetylsalicylic acid as an antiaggregative agent after starting ibuprofen administration is possible).

Combination with ethanol, GCS, corticotropin increases the risk of gastrointestinal erosive ulcers.

Ibuprofen increases the effect of direct (heparin) and indirect (coumarin and indandion derivatives) anticoagulants, thrombolytic agents (alteplase, anistreplase, streptokinase, urokinase), antiaggregants, colchicine – the risk of hemorrhagic complications increases.

Accelerates the hypoglycemic effect of insulin and oral hypoglycemic drugs.

Allows the effects of hypotensive drugs and diuretics (due to inhibition of renal PG synthesis).

increases blood concentrations of digoxin, lithium drugs and methotrexate.

Caffeine increases the analgesic effects of ibuprofen.

Cyclosporine and gold drugs increase nephrotoxicity.

Cefamandol, cefoperazone, cefotetan, valproic acid, plikamycin increase the incidence of hypoprothrombinemia.

Antacids and colestyramine decrease absorption of the drug.

Myelotoxic drugs contribute to the hematotoxicity of the drug.

Special Instructions

Contraindications

Side effects

Overdose

Symptoms: gastrointestinal disorders (diarrhea, nausea, vomiting, anorexia, epigastric pain), increased PV, bleeding after 12-48 hours, lethargy, drowsiness, depression, headache, tinnitus, impaired consciousness, heart rhythm disturbances, BP decrease, hepato- and nephrotoxicity symptoms, seizures, possible hepatonecrosis development.

If overdose is suspected, seek medical attention immediately.

Treatment: gastric lavage during the first 4 hours; alkaline drinking, forced diuresis; administration of activated charcoal, administration of SH-group donators and precursor of glutathione synthesis – methionine – 8-9 hours after overdose and N-acetylcysteine orally or v/v 12 hours later, antacids; hemodialysis; symptomatic therapy. The need for additional therapeutic measures (further methionine administration, intravenous N-acetylcysteine) is determined depending on the concentration of paracetamol in blood, as well as on the time elapsed after its administration.

Pregnancy use

Similarities