Hepone, lyophilizate 2 mg

Pharmacotherapeutic group:immunomodulatory agent

ATX code: L03

Pharmacological properties

Pharmacodynamics

Hepon has immunomodulatory and antiviral effects:

• causes production of alpha- and beta- interferons;
• mobilizes and activates macrophages;
• restricts the production of pro-inflammatory cytokines (interleukins 1, 6, 8 and tumor necrosis factor);
• stimulates the production of antibodies to various antigens of infectious nature;
• increases CD4⁺ T cells and NK cells;
• increases the functional activity of neutrophils and CD8⁺ T cells, which are key links in the body’s defense against bacteria, viruses and fungi;
• inhibits viral replication.

Because of these pharmacological properties, Hepone increases the resistance of the body against infections caused by viruses, bacteria and fungi. Hepon has an anti-inflammatory effect within 1-2 days after application.

Pharmacokinetics of the drug has not been studied due to its peptide nature.

Indications

Composition

Active ingredient:
threonyl-glutamyl-lysyl-arginyl-arginyl-glutamyl-threonyl-valyl-glutamyl-arginyl-glutamate (Hepone) 1mg, 2 mg

How to take, the dosage

It is used topically, externally.

Before use the drug is dissolved in water for injection (for external use of the drug, i.e. for skin treatment) or in 0.9% sodium chloride solution (for local use of the drug, i.e. for treatment of mucous membranes).

The way of preparing the drug before use:

Table 1

Hepone, mg

.How to use

Hepone 0.02% solution

1

2

1

2

Water for injection, ml

strong>

externally

–

–

2.5

5

0.9% sodium chloride solution, ml

locally

5

10

–

–

Special Instructions

Synopsis

Contraindications

Side effects

Overdose

Pregnancy use