Gentamicin-ACOS, ointment 0.1% 15 g

Gentamitsin-Acos has bactericidal effect.

Actively penetrates through the cell membrane of bacteria and irreversibly binds with 30S subunit of bacterial ribosomes and thus inhibits the synthesis of the pathogen protein.

It is highly active against aerobic gram-negative bacteria as well as against aerobic gram-positive cocci and some strains.

Neisseria meningitidis, Treponema pallidum, some strains of Streptococcus spp. are resistant to Gentamicin, anaerobic bacteria.

Indications

Bacterial infections of the skin and soft tissues caused by sensitive microflora – pyoderma (including gangrenous) superficial folliculitis furunculosis sycosis paronychia.

Infected: dermatitis (including contact seborrheic and eczematous) ulcers (including varicose veins) wounds (including sluggish surgical wounds) burns (including plants) insect bites skin abscesses and cysts “vulgar” acne; secondary bacterial infection in fungal and viral skin infections.

Pharmacological effect

Broad-spectrum aminoglycoside antibiotic.

Gentamicin-Akos has a bactericidal effect.

Actively penetrating the bacterial cell membrane, it irreversibly binds to the 30S subunit of bacterial ribosomes and, thereby, inhibits the synthesis of the pathogen protein.

Highly active against aerobic gram-negative bacteria, also against aerobic gram-positive cocci, some strains.

Neisseria meningitidis, Treponema pallidum, some strains of Streptococcus spp., and anaerobic bacteria are resistant to Gentamicin.

Special instructions

Treatment is carried out under the supervision of an antibiogram of the drug, since long-term use may lead to the development of resistance. In such cases, it is necessary to note the treatment and begin appropriate therapy.

When applied to large surfaces of the skin, the possibility of a resorptive effect must be taken into account, especially in patients with chronic renal failure.

If there is no therapeutic effect within 1 week, you should consult your doctor.

Active ingredient

Gentamicin

Composition

100 g ointment contains:

Active substance: gentamicin sulfate (in terms of gentamicin) – 0.1 g

Excipients: solid petroleum paraffin – 5.0 g, medical vaseline – up to 100 g.

Contraindications

Hypersensitivity (including a history of other aminoglycosides).

With caution:

Side Effects

Allergic reactions: local – skin rash, itching, skin hyperemia, burning sensation; rarely generalized – fever, angioedema, eosinophilia.

When absorbed from large surfaces, systemic effects may develop.

Interaction

At the same time or immediately after the end of the course of treatment with Gentamicin (when used on large surfaces and/or for a long time), antimicrobials and other drugs that have an otonephrotoxic effect should not be prescribed.

Storage conditions

List B. At temperatures from 8 °C to 15 °C.

Keep out of the reach of children.

Shelf life

3 years

Manufacturer

Sintez, Russia