Fungoderil, 1% 15 ml
€15.32 €12.76
Pharmacotherapeutic group: Antifungal agent
Pharmacodynamics
Naphtifine is an antifungal agent for external use, belonging to the class of allilamines. The mechanism of action is related to inhibition of squalene-2,3-epoxidase, which reduces the formation of ergosterol, a component of the cell wall of the fungus.
Active against dermatophytes such as Trichophyton, Epidermophyton, Microsporum, molds (Aspergillus spp.), yeasts (Candida spp., Pityrosporum) and other fungi (such as Sporothrix schenckii). Against dermatophytes and aspergillus naphthifin acts fungicidal.
Against yeast fungi naphthifin has fungicidal or fungistatic activity depending on the microorganism strain. It has antibacterial activity against Gram-positive and Gram-negative microorganisms that may cause secondary bacterial infections. It has anti-inflammatory effect, which contributes to the rapid disappearance of inflammatory symptoms, especially itching.
Pharmacokinetics
Indications
- Fungal infections of the skin and skin folds (tinea corporis, tinea inquinalis)
- finger mycoses (tinea manum, tinea pedum)
- fungal nail infections (onychomycoses)
- dermatomycoses (with or without associated itching)
.
Active ingredient
Naftifin
Composition
Active ingredient: naphthyphine hydrochloride 10.0 mg;
Excipients: propylene glycol, ethanol 96%, purified water.
How to take, the dosage
Externally.
In case of skin lesions
Apply once a day to the affected skin surface and its surrounding areas (about 1 cm of healthy skin around the edges of the affected area) after thoroughly cleaning and drying them.
The therapy duration is 2-4 weeks in dermatomycosis (up to 8 weeks if necessary); 4 weeks in candidiasis.
In case of nail lesions
Apply on the affected nail. Before the first application, remove the affected part of the nail with a pair of scissors or a nail file as much as possible.
The duration of therapy for onychomycosis is up to 6 months.
To prevent recurrence, treatment should be continued for at least 2 weeks after clinical symptoms have disappeared.
Special Instructions
The drug is not intended for use in ophthalmology. Avoid contact of the drug with the eyes.
Course treatment is required to achieve therapeutic effect. The drug is effective in the treatment of mycosis affecting areas of the skin with hyperkeratosis and also in hair growth areas.
Synopsis
Transparent solution from colorless to light yellow color with odor of ethanol.
Contraindications
Hypersensitivity to naphthyphine or other ingredients of the drug; pregnancy and breastfeeding (safety and effectiveness of use have not been established), application to the wound surface.
Cautions
Childhood (experience with clinical use limited).
Side effects
In some cases there may be local reactions: dry skin, skin hyperemia (redness), burning.
Side effects are reversible and do not require withdrawal of treatment.
If any of the side effects listed in the instructions are aggravated, marked any other side effects not specified in the instructions, you should immediately inform the doctor.
Pregnancy use
The use of the drug is contraindicated in pregnancy and during breastfeeding (safety and efficacy of naphthifin in this category of patients has not been studied).
Similarities
Exoderil, Mycoderil, Mizol, Naftoderil, Naftifin
Weight | 0.057 kg |
---|---|
Shelf life | 2 years. Do not use after the expiration date. |
Conditions of storage | At a temperature not exceeding 30 ° C. Store out of the reach of children. |
Manufacturer | Nizhpharm AO, Russia |
Medication form | solution for external use |
Brand | Nizhpharm AO |
Related products
Buy Fungoderil, 1% 15 ml with delivery to USA, UK, Europe and over 120 other countries.