Forliver Help, tablets 100 mg 30 pcs

The main active component of the drug is the sum of flavolignans (silymarin) derived from fruits of milk thistle Silybum marianum (L.) Gaerth of Asteraceae (including silybinin, isosilibinin, silydianin, silicristin).

Pharmacodynamics

The drug has hepatoprotective and antitoxic effect. The therapeutic effect is due to the effect on hepatocyte metabolism. It activates synthesis of proteins and enzymes in hepatocytes, stabilizes the membrane of hepatocytes, inhibits penetration of toxins into liver cells, inhibits dystrophic and potentiates regenerative processes of the liver.

Pharmacokinetics

The adsorption of silibinin is quite low and only 2-3% is excreted with bile during the first 24 hours. As a result of cleavage by the intestinal microflora, up to 40% of the silibinin excreted with bile is reabsorbed, resulting in entero-hepatic circulation. The peak of silybinin in plasma after oral administration is reached after 3-4 hours. Silymarin is eliminated from the body mainly with the bile and, to a lesser extent, by the kidneys. The half-life is 6 to 8 hours. It does not accumulate in the body.

Indications

Active ingredient

Composition

How to take, the dosage

Interaction

Special Instructions

Impact on ability to drive and operate machinery

The use of the drug does not influence the ability to perform potentially hazardous activities requiring high concentration and quick psychomotor reactions (driving vehicles, operating moving mechanisms, operator’s work).

Contraindications

Patients with diabetes, children from 12 years.

Side effects

Overdose

Pregnancy use

Similarities