Fluimucil, 200 mg sachet 20 pcs

Fluimucil is a mucolytic drug with antioxidant properties. It dilutes sputum, increases its volume and facilitates its separation.
The action of acetylcysteine is associated with the ability of its sulfhydryl groups to break intra- and intermolecular disulfide bonds of acidic mucopolysaccharides of sputum, which leads to depolarization of mucoproteins and reduction of sputum viscosity.

Contains activity in the presence of purulent sputum.

It has an antioxidant effect due to the presence of a SH-group capable of neutralizing electrophilic oxidative toxins.

It also has anti-inflammatory action (due to the suppression of free radicals and active oxygen-containing substances responsible for the development of inflammation in lung tissue).

Indications

Bronchitis, Gymorrhitis, Otitis, Laryngitis, Tracheitis, Cough, Chronic Obstructive Pulmonary Disease, Bronchial asthma, Lung inflammation (pneumonia), Sinusitis, Colds

Respiratory diseases accompanied by sputum formation of high viscosity (acute and chronic bronchitis, pneumonia, bronchiectasis, cystic fibrosis, bronchial asthma), to ease the departure of mucus in sinusitis.

The diseases of the respiratory system, accompanied by sputum formation of high viscosity.

Active ingredient

Acetylcysteine

Composition

One bag contains:
active ingredient:
acetylcysteine – 200 mg;
excipients:
aspartame 25 mg,
betacarotene 12.3 mg,
orange flavoring 100 mg,
sorbitol 662.7 mg.

How to take, the dosage

Pellets for preparation of oral solution are dissolved in 1/3 cup of water.

Adults and children over 6 years of age – 200 mg 2-3 times a day.

In newborns, only if there are vital indications and at a dose of 10 mg/kg under close medical supervision. Children of the first year of life are given the resulting solution to drink from a spoon or feeding bottle. Children from 1 to 2 years of age are given 100 mg 2 times a day, from 2 to 6 years of age 200 mg 2 times a day or 100 mg 3 times a day.

The duration of treatment should be estimated individually. In acute conditions, the duration of treatment is from 5 to 10 days and up to several months in the treatment of chronic diseases (according to the doctor’s recommendation).

Interaction

Combined use of acetylcysteine with cough suppressants may increase sputum stasis due to suppression of the cough reflex.

In concomitant use with such antibiotics as tetracyclines (excluding doxycycline), ampicillin, amphotericin B, they may interact with the thiol group of acetylcysteine, which leads to decreased activity of both drugs. Therefore, the interval between doses of these drugs should be at least 2 hours.

The simultaneous use of acetylcysteine and nitroglycerin may cause a marked decrease in blood pressure and headache.

The concomitant use of acetylcysteine and carbamazepine may cause subtherapeutic levels of carbamazepine.

Activated charcoal may decrease the effects of acetylcysteine.

Acetylcysteine eliminates the toxic effects of paracetamol.

Acetylcysteine can affect the results of colorimetric determination of salicylates.

Acetylcysteine may affect urinary ketone analysis.

Special Instructions

Patients with bronchial asthma and obstructive bronchitis should only be prescribed Flumucil if adequate sputum drainage is ensured.

The oral dosage forms contain aspartame, so they should not be prescribed to patients with phenylketonuria.

When dissolving the drug, use glassware and avoid contact with metal and rubber surfaces.

When opening the bag with pellets the smell of sulfur is possible, which is the smell of the active ingredient and not an indication of poor quality of the drug.

Contraindications

Hypersensitivity to acetylcysteine, acute gastric and duodenal ulcer.

The drug should be prescribed with caution in patients with liver and kidney diseases.

Side effects

The digestive system: rarely – heartburn, nausea, vomiting, diarrhea, stomatitis.

Allergic reactions: rare – skin rash, itching, urticaria, bronchospasm.

Others: rare – nasal bleeding, tinnitus, collapse, decreased platelet aggregation.

Local reactions: when parenteral use, mild burning sensation at the injection site is possible; when inhaled, reflexive cough, local airway irritation, stomatitis, rhinitis; bronchospasm is rare (in this case bronchodilators should be prescribed).

Overdose

Acetylcysteine at a dose of 500 mg/kg/day does not cause signs and symptoms of overdose.

Symptoms
The following symptoms may occur: nausea, vomiting and diarrhea.

Treatment: there is no specific antidote, treatment is symptomatic.

Pregnancy use

Pregnant and breastfeeding use is possible only if the expected benefit to the mother outweighs the potential risk to the fetus or baby.

Similarities

Atsc, Atsc 200, Atsc-long, Acetylcysteine, Fluimucil, Acetylcysteine Canon, Espa-Naz, Eifa AC