Fluimucil, 20 mg/ml 100 ml

Sinusitis, Lung inflammation (pneumonia), Sore throat, Otitis, Laryngitis, Bronchitis, Gymorrhitis, Cough, Colds, Chronic obstructive pulmonary disease, Tracheitis, Bronchial asthma

Difficulty with sputum discharge (bronchitis, tracheitis, bronchiolitis, pneumonia, bronchiectatic disease), cystic fibrosis, lung abscess, pulmonary emphysema, laryngotracheitis, interstitial lung diseases, bronchial asthma, pulmonary atelectasis (due to blockage of bronchi with a mucous plug), catarrhal and purulent otitis, sinusitis, including maxillary sinusitis, sinusitis, and tonsillitis.including maxillary sinusitis, removal of viscous secretion from the airways in post-traumatic and post-operative states, paracetamol poisoning (as an antidote).

Active ingredient

Composition

100 ml of the solution contain

the active ingredient – acetylcysteine 2 g,

Point of oral solution, 20 mg/ml

complementary substances:

methylparahydroxybenzoate,

sodium benzoate,

p>sodium edetate,

sodium carmellose,

sodium saccharinate,

How to take, the dosage

For oral administration.

Adults: 5 ml of oral solution 40 mg/ml in 1-3 doses (corresponds to 200 – 600 mg of acetylcysteine per day).

Children:

– Children from 2 to 5 years: 5 ml of 20 mg/ml oral solution in 2-3 doses (corresponding to 200-300 mg of acetylcysteine per day)

– Children and adolescents from 6 to 14 years: 5 ml of 20 mg/ml oral solution in 3-4 doses (corresponding to 300-400 mg of acetylcysteine per day) or 5 ml of 40 mg/ml oral solution in 2 doses (corresponding to 400 mg of acetylcysteine per day)

– Children over 14 years: 5 ml of 40 mg/ml oral solution in 1-3 doses (corresponding to 200 to 600 mg of acetylcysteine per day).

In case of paracetamol overdose: in the first 10 hours after ingestion, as soon as possible administer Fluimucil at the rate of 140 mg/kg, further at 70 mg/kg every 4 hours, for 1-3 days.

Interaction

Combined use of acetylcysteine with cough suppressants may increase sputum stasis due to suppression of the cough reflex.

In concomitant use with such antibiotics as tetracyclines (excluding doxycycline), ampicillin, amphotericin B, they may interact with the thiol group of acetylcysteine, which leads to decreased activity of both drugs. Therefore, the interval between doses of these drugs should be at least 2 hours.

The simultaneous administration of acetylcysteine and nitroglycerin may increase the vasodilator and disaggregant effect of the latter.

If concomitant administration of acetylcysteine and nitroglycerin is necessary, patients should have their hypotension monitored, which may be severe, and should be warned of the possibility of headache or headache development. Activated charcoal may decrease the effectiveness of acetylcysteine.

Acetylcysteine reverses the toxic effects of paracetamol.

Special Instructions

Patients with bronchial asthma and obstructive bronchitis acetylcysteine should be prescribed with caution due to the possibility of bronchospasm. If bronchospasm occurs, treatment with acetylcysteine should be stopped immediately.The use of acetylcysteine mainly at the beginning of treatment may cause liquefaction of bronchial secretion and increase its volume. If the patient is unable to expectorate effectively, postural drainage or bronchial aspiration is necessary.

The drug Fluimucil contains aspartame, a source of phenylalanine. This must be taken into account in patients with phenylketonuria.

The drug also contains sorbitol and sucrose which should not be used in patients with hereditary fructose intolerance or impaired glucose-galactose absorption or sucrose-isomaltase deficiency.

Patients with a history of gastric or duodenal ulcer, especially in cases of concomitant use of other drugs that irritate the gastric mucosa, are advised to use with caution.

Particular effects on the ability to drive vehicles and potentially dangerous mechanisms

Contraindications

Hypersensitivity, peptic ulcer and duodenal ulcer in the acute stage.

Side effects

Gastrointestinal tract disorders: nausea, vomiting, heartburn, feeling of fullness of the stomach, stomatitis.

Allergic reactions: skin rash, itching, urticaria, bronchospasm (mainly in patients with bronchial hyperresponsiveness).

Others: drowsiness, fever; rarely – tinnitus; reflexive cough, local airway irritation, rhinorrhea (when inhaled); burning sensation at the injection site (when parenterally administered).

Overdose

Symptoms: Overdose may manifest as gastrointestinal symptoms such as nausea, vomiting and diarrhea.

Treatment: symptomatic therapy. There is no specific antidote.

Similarities