Florin forte, capsules 30 pcs

Pharmacotherapeutic group
Probiotic
ATCode A07FA

Biological properties
Florin® forte restores the normal microflora of the human body, inhibits the activity of pathogens of infectious diseases of the gastrointestinal tract and upper respiratory tract due to the living probiotic bacteria included in the preparation: Bifidobacteria (Bifidobacterium bifidum), sorbed in the form of microcolonies, and lactobacilli (Lactobacillus plantarum). The combined action of bifidobacteria and lactobacteria sorbed on activated carbon in the form of microcolumns provides accelerated normalization of quantitative and qualitative composition, metabolic and functional activity of microflora, enhance suppressive action on pathogens of acute intestinal infections, acute respiratory-viral infections and their elimination from the body, increases nonspecific resistance.

.Bifidobacteria contained in the product have antimicrobial activity due to antagonistic activity against pathogenic and conditionally pathogenic microorganisms, immunomodulatory activity – they stimulate the synthesis of immunoglobulins, interferons, cytokines, participate in the formation of local immunity, stimulate mucous membrane repair and parietal digestion, produce enzymes, short-chain fatty acids and lactic acid. Bifidobacteria are biosorbents, neutralize toxins, accumulate toxic substances and remove them from the body. Lactobacillus inhibit the growth of pathogens through the production of lactic acid, hydrogen peroxide, lysozyme, are involved in the metabolism of proteins, fats, carbohydrates, nucleic and bile acids, activate the immune system, prevent the formation of long-term intestinal diseases by increasing the overall resistance of the body. Lactobacillus has hypocholesterolemic effect, reduces the redox potential, binds harmful oxygen radicals for bifidobacteria. Lactobacillus and bifidobacteria have strong suppressive effect against rotavirus and hemolytic Escherichia coli, produce antibiotic-like substances – bacteriocins, are involved in the synthesis of vitamins, use lactose during life as the main source of food.
It is not absorbed into the bloodstream.

Indications

– diseases accompanied by abnormal intestinal microflora with a deficit of bifidobacteria, lactobacilli or normal intestinal bacilli,
– acute intestinal infections due to rotaviruses and / or conditionally pathogenic microflora,
– acute infections of unspecified etiology,
– acute intestinal infections due to rotaviruses and/or conditionally pathogenic microflora.- Acute intestinal infections caused by rotaviruses and/or conditionally pathogenic microflora,
– Acute intestinal infections of unknown etiology,
– Acute respiratory diseases of both viral and microbial origin,– Chronic diseases of the gastrointestinal tract (GIT), including those with detected hemolytic E. coli and associations of opportunistic pathogens in high titers,
– restoration of intestinal normoflora during convalescence after a disease,
– dysbacteriosis of various etiologies.

Active ingredient

Bifidobacterium bifidum, Lactobacillus plantarum

Composition

One capsule contains:

Active ingredients: bifidobacteria B.bifidum sorbed on activated carbon – at least 50 million colony-forming units (5×107 CFU), lactobacilli L.
Supplementary substances: components of the drying medium (sucrose-gelatin) – sucrose 8.08-8.24 mg, gelatin 1.07-1.09 mg, activated carbon 2.73-2.79 mg, magnesium stearate l-10 mg, lactose monohydrate up to 0.20 g.
capsule shell composition: capsule body – titanium dioxide (white) 1.0-2.0%, gelatin to 100%, capsule cap – titanium dioxide 1.0-2.0%, iron oxide (yellow) 0.05-1.8%, gelatin to 100%.

How to take, the dosage

The drug is intended to be used in adults and children from the first days of life (including premature babies).
Adults take 2 capsules 3 times a day.
In children under 6 months: 1 capsule 2 times a day.
In children from 6 months to 3 years: 1 capsule 3 times a day.
In children from 3 years and older: 1 capsule 3 – 4 times a day. Course of treatment:
– in diseases accompanied by a violation of normal intestinal microflora 10 – 15 days,
– in acute intestinal infections 5 – 7 days,
– in acute respiratory diseases 5 – 10 days,– with chronic gastrointestinal diseases 10 – 15 days,
– in convalescence period after the diseases 10 – 15 days,
– with dysbacteriosis 10 – 15 days.

Florin® forte is taken orally with meals, with water when necessary, independently of meals. For children and patients who cannot swallow the whole capsule, the capsule is opened. The contents of the capsule are mixed with a liquid food, preferably a fermented dairy product. You can mix the contents of the capsule with 5-30 ml of boiled water at room temperature in a spoon or glass, which forms a turbid suspension with particles of sorbent black. The resulting aqueous suspension should be drank without achieving complete dissolution.

Interaction

When taking Florin® Forte with vitamins (especially group B), the effect of the drug is enhanced. When taking antibiotics, the recommended interval between taking antibiotics and Florin® Forte is 3 – 4 hours.

Special Instructions

The drug does not affect the ability to drive vehicles and mechanisms.

Synopsis

Solid gelatin capsules. The body of the capsule is white, the cap is yellow. The contents of the capsule is a powder with a faint sour odor of light gray or dark gray color with black flecks.

Contraindications

Congenital lactase deficiency. Impaired glucose-galactose absorption. Individual intolerance of the drug.

Side effects

Not established.

Overdose

No cases of overdose were observed.

Pregnancy use

The drug is approved for use in women during pregnancy and breastfeeding.