Florin forte, 50 mln coe+50 mln coe 0.85 g 20 pcs

Pharmacotherapeutic group
Probiotic
ATX Code A07FA

Biological properties
Florin® forte restores the normal microflora of the human body, inhibits the activity of pathogens of infectious diseases of the gastrointestinal tract and upper respiratory tract due to the living probiotic bacteria included in the preparation: Bifidobacteria (Bifidobacterium bifidum), sorbed in the form of microcolonies, and Lactobacillus plantarum.

The combined action of bifidobacteria and lactobacteria sorbed on activated carbon in the form of microcolumns provides accelerated normalization of the quantitative and qualitative composition, metabolic and functional activity of the microflora, increases suppressive action against pathogens of acute intestinal infections, acute respiratory viral infections and their removal from the body, increases non-specific resistance.
Bifidobacteria contained in the preparation have antimicrobial action due to antagonistic activity against pathogenic and conditionally pathogenic microorganisms, immunomodulatory action – they stimulate synthesis of immunoglobulins, interferons, cytokines, take part in forming local immunity, enhance mucous membrane reparation and near wall digestion, produce enzymes, short-chain fatty acids and lactic acid. Bifidobacteria are biosorbents; they neutralize toxins, accumulate toxic substances and remove them from the body.

Lactobacteria inhibit the growth of pathogens through the production of lactic acid, hydrogen peroxide, lysozyme, are involved in the metabolism of proteins, fats, carbohydrates, nucleic and bile acids, activate the immune system, prevent the formation of prolonged forms of intestinal diseases by increasing the overall resistance of the body. Lactobacillus has hypocholesterolemic effect, reduces redox potential, and binds oxygen radicals that are harmful to bifidobacteria.
Lactobacillus and bifidobacteria have strong suppressive effect against rotavirus and hemolytic Escherichia coli, produce antibiotic-like substances – bacteriocins, are involved in the synthesis of vitamins, use lactose during life as the main source of nutrition.

Indications

– diseases accompanied by disruption of the normal intestinal microflora with a deficiency of bifidobacteria, lactobacilli or normal E. coli,
-acute intestinal infections caused by rotaviruses and/or opportunistic microflora,
-acute intestinal infections of unknown etiology,
-acute respiratory diseases of both viral and microbial origin,
-chronic diseases of the gastrointestinal tract (GIT), including those with identified hemolytic Escherichia coli and associations of opportunistic microorganisms in high titers,
– restoration of normal intestinal flora during the period of convalescence after illnesses,
– dysbacteriosis of various etiologies.

Pharmacological effect

Pharmacotherapeutic group
Probiotic
ATX code A07FA

BIOLOGICAL PROPERTIES
Florin® forte restores the normal microflora of the human body, suppresses the vital activity of pathogens of infectious diseases of the gastrointestinal tract and upper respiratory tract due to the live probiotic bacteria included in the drug: bifidobacterium bifidum, sorbed in the form of microcolonies, and lactobacilli (Lactobacillus plantarum).

The combined effect of bifidobacteria and lactobacilli sorbed on activated carbon in the form of microcolonies ensures accelerated normalization of the quantitative and qualitative composition, metabolic and functional activity of microflora, enhances the suppressive effect on pathogens of acute intestinal infections, acute respiratory viral infections and their removal from the body, increases the nonspecific resistance of the body.
Bifidobacteria that are part of the drug have an antimicrobial effect due to antagonistic activity towards pathogenic and conditionally pathogenic microorganisms, an immunomodulatory effect – they stimulate the synthesis of immunoglobulins, interferons, cytokines, participate in the formation of local immunity, activate the repair of mucous membranes and parietal digestion, produce enzymes, short-chain fatty acids, lactic acid. Bifidobacteria are a biosorbent, neutralize toxins, accumulate toxic substances and remove them from the body.

Lactobacilli suppress the growth of pathogens by producing lactic acid, hydrogen peroxide, lysozyme, participate in the metabolism of proteins, fats, carbohydrates, nucleic and bile acids, activate the immune system, and prevent the formation of protracted forms of intestinal diseases by increasing the overall resistance of the body. Lactobacilli have a hypocholesterolemic effect, reduce the redox potential, and bind oxygen radicals harmful to bifidobacteria.
Lactobacilli and bifidobacteria have an enhanced suppressive effect on rotaviruses and hemolytic Escherichia coli, produce antibiotic-like substances – bacteriocins, participate in the synthesis of vitamins, and use lactose in the process of life as the main source of nutrition.

Special instructions

The drug does not affect the ability to drive vehicles or machinery.

Active ingredient

Bifidobacterium bifidum, Lactobacillus plantarum

Composition

One package contains
active substances: bifidobacteria sorbed on activated carbon
– at least 50 million colony-forming units (5×107 CFU), lactobacilli – at least 50 million colony-forming units (5×107 CFU), excipient: lactose monohydrate – up to 0.85 g.

Pregnancy

The drug is approved for use by women during pregnancy and breastfeeding. There are no special conditions for admission.

Contraindications

Congenital lactase deficiency. Impaired absorption of glucose-galactose. Individual intolerance to the drug.

Side Effects

Not installed.

Interaction

When Florin® forte is taken simultaneously with vitamins (especially group B), the effect of the drug is enhanced. When taking antibiotics, the recommended interval between taking the antibiotic and Florin® forte is 3–4 hours.

Overdose

There were no cases of overdose.

Storage conditions

Store at temperatures from 2 to 10 °C.
Keep out of reach of children
Not suitable for use after the expiration date, if the appearance has changed, if the integrity of the package has been compromised, or if the markings on the primary or secondary packaging are unclear.

Shelf life

2 years.

Manufacturer

ProBioPharm, Russia