Ferlatum Fol, 15 ml 10 pcs

According to the instructions to Furlatum, this drug has a pronounced anti-anemic effect. The active ingredient of the drug is iron succinylate protein. This substance is a complex compound in which trivalent iron atoms are arranged in the environment of a semi-synthetic protein carrier, which does not cause irritation and damage to the mucosa of the gastrointestinal tract.

The main function of iron is to deliver oxygen to all body tissues. It is part of hemoglobin, myoglobin, iron-containing enzymes-cytochorms, catalyzes oxidative reactions, is responsible for electron transport, hydroxylation and other metabolic processes.

Ferlatum analogues include such drugs as Ferlatum Fol and Iron Protein Succinylate.

Indications

– Treatment of latent and clinically significant iron deficiency (iron deficiency anemia) and folates;
– Preventive therapy for iron and folate deficiency during pregnancy, lactation, active growth; after prolonged bleeding, against the background of inadequate and unbalanced nutrition.

Pharmacological effect

ATX code: B03AB09.

Pharmacological properties:
Ferlatum Fol is a preparation of iron and calcium folinate, replenishes the lack of iron and folates in the body.
The main function of iron is to transport oxygen to tissues. Iron is part of hemoglobin, myoglobin, iron-containing enzymes-cytochromes, transfers electrons and works as a catalyst for oxidation reactions, hydroxylation and other metabolic processes.
Ferlatum Fol contains iron protein succinylate, which is a complex compound where ferric iron atoms (Fe3+) are surrounded by a semi-synthetic protein carrier that prevents damage to the gastric mucosa. The protein carrier redissolves in the duodenum, releasing iron at the site of best absorption.
Ferric iron enters the blood from the intestines through active absorption, which explains the impossibility of overdose and poisoning.
Calcium folinate is the calcium salt of folinic acid, which replenishes the lack of folate in the body.

Special instructions

The continuous period of use of Ferlatum Fola should not exceed 6 months, with the exception of cases of chronic blood loss (menorrhagia, hemorrhoids, etc.) and pregnancy.

Does not affect engagement in potentially hazardous activities that require increased concentration and speed of psychomotor reactions (including driving).

The drug should be used with caution in patients suffering from milk protein intolerance, who may experience an allergic reaction.

Ferlatum Fol contains sorbitol, so patients suffering from hereditary fructose intolerance should not use the drug.

Active ingredient

Iron protein succinylate

Composition

1 bottle (15 ml) contains:
Active substance: iron protein succinylate – 800 mg (equivalent to 40 mg Fe+3)
Excipients: sorbitol – 1400 mg, propylene glycol – 1000 mg, sodium methyl parahydroxybenzoate – 45 mg, sodium propyl parahydroxybenzoate – 15 mg, cherry flavor (concentrated wild black cherry flavor, vanillin, amyl acetate, small amounts of other esters, benzaldehyde, clove bud oil, propylene glycol, diethylene glycol monoethyl ether, water) – 60 mg, sodium saccharinate – 15 mg, purified water – up to 15 ml.
Each dispenser cap (container cap) contains:
Active substance: calcium folinate pentahydrate – 0.235 mg (equivalent to 0.200 mg calcium folinate or 0.185 mg folinic acid);
Excipients: mannitol – 99.8 mg.

Pregnancy

The use of Ferlatum Fol is especially recommended for the prevention and treatment of iron and folate deficiency that develops during pregnancy and lactation.

Contraindications

– Hypersensitivity to the drug;
– Iron overload (hemochromatosis);
– Impaired iron utilization (lead anemia, sideroachrestic anemia);
– Non-iron deficiency anemia (hemolytic anemia; megaloblastic anemia caused by vitamin B12 deficiency);
– Chronic pancreatitis;
– Cirrhosis of the liver.

With caution:
Caution should be exercised in patients with: gastric ulcer and duodenal ulcer, malabsorption due to pathology of the small intestine (enteritis, malabsorption syndrome, resection of the small intestine, Billroth II gastric resection including the duodenum).

Side Effects

In rare cases, gastrointestinal disorders may occur, which disappear when the dose is reduced or the drug is discontinued.

Interaction

There was no interaction of Ferlatum Fola with other drugs used simultaneously.

Iron absorption can be increased with simultaneous administration of more than 200 mg of ascorbic acid and reduced with the use of antacids. Chloramphenicol causes a delayed response to iron therapy.

There was no pharmacological interaction during concomitant treatment with H2 receptor antagonists.

Some antitumor and antileukemic drugs (aminopterin, methotrexate and other pterin derivatives) behave as folate antagonists.

Overdose

To date, no signs of intoxication or excess intake of the drug Ferlatum Fol into the body have been described.

Storage conditions

At a temperature not higher than 25 oC. Keep out of the reach of children!

Shelf life

2 years. Do not use a drug that has expired.

Manufacturer

Italfarmaco S.A., Spain