Esslial forte, capsules 300 mg 90 pcs
€51.31 €42.76
Essential phospholipids are the basic elements of the structure of the liver cell envelope and cell organelles. In case of liver diseases there is always damage of liver cell membranes and their organelles, which leads to disturbances in activity of associated enzymes and receptor systems, deterioration of functional activity of liver cells and decreased ability to regenerate.
Phospholipids contained in the preparation
Esslial forte correspond in their chemical structure to endogenous phospholipids, but exceed the activity of endogenous phospholipids due to their higher content of polyunsaturated (essential) fatty acids.
Incorporation of these high-energy molecules into damaged sections of hepatocyte cell membranes restores integrity of hepatic cells and promotes regeneration.
Cis-double bonds of their polyunsaturated fatty acids prevent the parallel arrangement of hydrocarbon chains in phospholipids of cell membranes, the density of phospholipid structure of cell membranes of hepatocytes decreases, thus increasing their fluidity and elasticity and improving metabolism.
The formed functional blocks increase the activity of membrane-fixed enzymes and contribute to the normal physiological way of essential metabolic processes.
Phospholipids contained in the drug
Esslial forte regulates the metabolism of lipoproteins, transferring neutral fats and cholesterol to the sites of oxidation, mainly by increasing the ability of high density lipoproteins to bind to cholesterol.
Thus there is a normalizing effect on lipid and protein metabolism, the detoxifying function of the liver and phospholipid-dependent enzyme systems, which ultimately prevents the formation of connective tissue in the liver and promotes natural regeneration of liver cells.
Phospholipids excretion into the bile decreases the lithogenic index and stabilizes the bile
Indications
- Chronic hepatitis,
- cirrhosis of the liver,
- fatty liver dystrophy of various etiologies,
- alcoholic hepatitis,
- disorders of liver function in other somatic diseases.
- Pregnancy toxicosis,
- prevention of recurrence of gallstone formation,
- psoriasis (as adjuvant therapy),
- radiation syndrome.
- toxic liver injury,
Active ingredient
Phospholipids
Composition
1 capsule contains:
Active ingredient:
Lipoid PPL-400 – 400.0 mg, in terms of polyunsaturated phospholipids from soy lecithin (PPL fraction) – 300.0 mg, with an average content of L-α-phosphatidylcholine 76% – 228.0 mg.
Excipients:
Ethyl alcohol 95% – 4.0 mg.
Solid gelatin capsules № 0:
Contents of the capsule body: iron oxide dye black – 0,01%, iron oxide dye red – 0,01%, iron oxide dye yellow – 0,1714%, titanium dioxide – 3%, gelatin – up to 100%;
Composition of the capsule cap: iron oxide dye black – 0.53%, iron oxide dye red – 0.93%, iron oxide dye yellow – 0.2%, titanium dioxide – 0.3333%, gelatin – up to 100%
How to take, the dosage
Oral. The capsules should be taken as a whole with plenty of water (approximately 1 glass).
For adolescents over 12 years and weighing over 43 kg, as well as adults, Esslial forte is recommended to take 2 capsules – 3 times a day with meals.
As a rule, the duration of use is not limited.
Contraindications
Individual intolerance to phosphatidylcholine or other excipients of the drug.
Soy intolerance.
Childhood under 12 years of age (lack of sufficient evidence).
Side effects
The drug Esslial forte is usually well tolerated by patients.
The following definitions are used to evaluate the frequency of side effects:
very often (>1/10), often (>1/100 – <1/10),
not often (>1/1000 – <1/100),
rarely (>1/10000 – <1/1000),
very rare (<1/10000),
unknown frequency (according to available data it is impossible to determine the frequency of occurrence).
Gastrointestinal tract:
rarely – discomfort in the epigastric region, loose stools, nausea, gastralgia.
Allergic reactions: very rare – rash, exanthema, urticaria; unknown frequency – itching.
Similarities
Essenciale N, Essenciale forte N, Essential phospholipids, ES-FOS
Weight | 0.075 kg |
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Shelf life | 3 years. Do not use after the expiration date stated on the package. |
Conditions of storage | In the dark place at a temperature not exceeding 25 ºС. Keep out of reach of children. |
Manufacturer | Ozon, Russia |
Medication form | capsules |
Brand | Ozon |
Other forms…
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