Erinit, tablets 10 mg 50 pcs

Erinit is a venous vasodilator and has an antianginal effect. It stimulates the formation of nitric oxide in the vascular wall, which is an endothelial relaxing factor. Erinitis reduces preload (dilation of peripheral veins and reduction of blood flow to the right atrium) and postload (OPPS) on the heart; it reduces myocardial oxygen demand.

Restores blood flow through small endocardial vessels, improves – in epicardial coronary arteries, increases exercise tolerance in patients with CHD, angina pectoris. It decreases pressure in the small circle of the blood circulation.

As compared to nitroglycerin, Erinit has a slower but longer action (up to 10 hours). When taken orally, the beginning of the effect – in 30-45 minutes (when sublingual – in 15-20 minutes), the duration – 4-5 hours.

Indications

Angina

Preventing angina attacks.

Active ingredient

Pentaerythrityl tetranitrate

Composition

1 tablet contains:

the active ingredient:

erinitis 0.01 g

How to take, the dosage

Ingestion (1 hour before meals) 10-20 mg (1-2 tablets) 3-4 times a day, if necessary up to 40 mg 4 times a day, 80 mg 2 times a day can be prescribed.

To prevent nocturnal attacks of angina, 20 mg is prescribed before bedtime. The course of treatment usually lasts 2-4 weeks. Repeated courses are prescribed by a physician.

Interaction

In case of concomitant use with other drugs, it is necessary to consult with the attending physician.

Dihydroergotamine may reduce the antianginal effect of Erinitis. A combination of these drugs is not advisable.

The combination with propranololol is rational because the antianginal effect of Erinitis is increased.

Ethanol enhances the effects of Erinitis.

Special Instructions

The drug is of little use in controlling angina attacks due to slow onset of effect.

The use of ethanol during treatment should be excluded.

Long-term use may decrease therapeutic effect (due to development of tolerance).

If the drug is used once daily in combination with other antianginal agents, the risk of tolerance decreases.

Contraindications

• high sensitivity to the drug and other organic nitrates;
• explicit arterial hypotension;
• collapse;
• shock;
• acute myocardial infarction with orthostatic hypotension;
• cranial trauma;
cerebral circulatory disorders (especially hemorrhagic stroke);
• closed-angle glaucoma;
• pregnancy;
period of lactation;
• simultaneous use with PDE inhibitors;
• age below 18 years of age (efficacy and safety not established).

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Side effects

• Allergic reactions,
• headache,
• Tinnitus,
• dizziness,

nausea,

weakness,

tachycardia.

• nausea,
• weakness,
• tachycardia,
• excessive fatigue,
• anxiety,
• excessive sweating,
• reduction of BP,
• ortostatic hypotension
• sometimes there is bowel function disorder (diarrhea).

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Similarities

Erinita tablets