Dolonit-MosPharma, gel 30 g

The action of the drug is due to its constituent active ingredients: dimethyl sulfoxide, sodium heparin and dexpanthenol.
Dimethyl sulfoxide (DMSO)

Indications

Joint pain (arthralgia), Myalgia (muscle pain), Heaviness and pain in the legs, Swelling after injuries and operations, Hematomas, Trigeminal neuralgia, Varicose veins, Cramps of the calf muscles, Neuralgia, Swelling, Contusions

• Oedema, bruises and inflammation of soft tissues, muscles, tendons, tendon sheaths and ligaments after bruises, squeezes, injuries;
• closed injuries, contusions
• joint injuries with damage to ligaments
• .periarthritis of the shoulder and epicondylitis of the shoulder (“tennis players’ elbow”), tendinitis (tendonitis), tendovaginitis (inflammation of tendon sheaths), bursitis (inflammation of the mucous membrane of joints);
• acute neuralgia.

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Active ingredient

Sodium heparin, Dexpanthenol, Dimethyl sulfoxide

Composition

The gel for external use is colorless, transparent or slightly opalescent, homogeneous, with a characteristic odor.

Associates:

carbomer homopolymer type C – 1 g,

tromethamol – 0.2 g,

macrogoal glyceryl hydroxystearate – 0.9 g,

ethanol 95% – 38.06 g,

rosemary oil – 0.2 g,

pine needles oil – 0.25 g,

Lemon oil – 0.05 g,

Purified water – up to 100 g.

How to take, the dosage

The drug is applied with a thin superficial layer to the skin over the affected area of soft tissues, joints or tendons (edema, hematoma, inflammation, trauma) and is evenly distributed with light rubbing movements.

Interaction

Topical use of other drugs simultaneously with the drug Dolonit-MosFarma promotes a sharp increase in their permeability through the skin.

In concomitant use with the nonsteroidal anti-inflammatory drug sulindac peripheral neuropathy may develop (due to the presence of dimethylsulfoxide in the drug Dolonit-MosPharma).

Special Instructions

The product is economical, penetrates the skin quickly and does not leave a greasy layer on the skin or stains on the laundry. Thanks to the alcohol (ethanol) contained, which evaporates after applying the gel, a pleasant cooling sensation is felt in the area where the product is applied. The pleasant cooling effect is intensified if the gel is kept in the refrigerator, as well as if it is used in hot weather (due to the increased evaporation of alcohol).

The area of skin to which the product is applied must be free of dirt, cosmetics, other medications and chemicals.

When bandages are used, wait a few minutes after applying the gel to allow time for the bulk of the gel to be absorbed and for the ethyl alcohol (ethanol) to evaporate. This is especially important when using a dressing that is poorly permeable to air.

You may experience increased photosensitivity of the skin during treatment with the drug, so you should limit intensive sunbathing and visits to a tanning bed during its use.

The treatment should be stopped if any skin reactions occur.

Because of the high absorption of dimethylsulfoxide, Dolonit-MosPharma should not be used in combination with other ointments and gels.

Please remember that contact with open wounds causes a pain reaction because the gel contains ethyl alcohol (ethanol).

Impact on ability to drive and operate machinery

The drug when applied topically does not affect the ability to drive vehicles and engage in other potentially dangerous activities requiring increased concentration and quick psychomotor reactions.

Contraindications

• High sensitivity to one of the gel components (active/supplementary substances);
• Severe hepatic and/or renal dysfunction;
• Bronchial asthma;
• Major cardiovascular disorders (functional class IV angina of the Canadian Heart Society classification, heart attack, stroke, severe generalized atherosis.Severe cardiovascular disorders (functional class IV angina by the classification of the Canadian Society of Cardiology, myocardial infarction, stroke, severe generalized atherosclerosis);
• pregnancy;
• breastfeeding period;
• children under 5 years of age.

The drug should not be used on the mucous membranes (eyes, nose, mouth), open wounds or damaged skin (e.g., conditions after radiation or severe sunburns, fresh postoperative scars).

Side effects

The drug is usually well tolerated, but in isolated cases local skin reactions (redness, itching and burning sensation at the application site) may occur, which usually gradually disappear during treatment.

In some cases, due to the content of DMSO or other ingredients of the drug, a generalized skin allergic reaction with urticaria and Quincke’s edema may occur.

In rare cases, some patients may have garlic breath due to dimethyl sulfide, a metabolite of dimethyl sulfoxide, when taking this medication.

This odor indicates that dimethylsulfoxide is well absorbed. Some patients may experience a change in taste sensation after application of the gel, which disappears after a few minutes.

In extremely rare cases, nausea, diarrhea, difficulty breathing, headache, and chills may occur if the product is applied to large areas of the body.

Overdose

Cases of overdose and poisoning of the drug have not been described.

Similarities

Dolobene