Dibicor, tablets 250 mg 60 pcs

Dibicor is metabolic.

Pharmacodynamics

Taurine is a natural product of the metabolism of sulfur-containing amino acids: cysteine, cysteamine, methionine. Taurine has osmoregulatory and membrane-protective properties, has a positive effect on the phospholipid composition of cell membranes, normalizes the exchange of calcium and potassium ions in cells.

Taurine has been shown to have inhibitory neurotransmitter properties, it has anti-stressor effect and may regulate the release of GABA, adrenaline, prolactin and other hormones, and regulate responses to them.

Participating in the synthesis of respiratory chain proteins in the mitochondria, taurine regulates oxidative processes and exhibits antioxidant properties and affects enzymes, such as cytochromes, responsible for the metabolism of various xenobiotics.

Dibicor^® improves metabolic processes in the heart, liver and other organs and tissues.

In chronic diffuse liver disease Dibicor^® increases blood flow and reduces the severity of cytolysis. Its treatment in case of cardiovascular insufficiency (CVI) decreases congestion in the small and large circulatory system: intracardiac diastolic pressure decreases, myocardial contractility increases (maximal contraction and relaxation rate, contractility and relaxation indices). The drug moderately decreases BP in patients with arterial hypertension and has practically no effect on BP in patients with CVD with lowered BP.

Dibicor^® reduces side effects from overdose of cardiac glycosides and slow calcium channel blockers; reduces hepatotoxicity of antifungal drugs. Improves performance under heavy physical exertion.

In diabetes mellitus, after about 2 weeks after the start of the drug Dibicor ^® blood sugar levels decrease. There is also a significant reduction of triglyceride concentration, to a lesser degree – of cholesterol level, reduction of plasma atherogenicity of lipids. Long-term use of the drug (about 6 months) showed improvement of the microcirculatory blood flow in the eye.

Pharmacokinetics

After a single administration of 500 mg of Dibicor^® the active ingredient (taurine) is detected in the blood in 15-20 min, C_max is reached in 1.5-2 h. The drug is completely eliminated after 24 hours.

Indications

Type 1 diabetes, Cardiac insufficiency, Type 2 diabetes

• cardiovascular insufficiency of various etiologies;

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• intoxication caused by cardiac glycosides;
• Chronic diabetes mellitus type 1;
• Chronic diabetes mellitus type 2, including.with moderate hypercholesterolemia;
• as a hepatoprotector in patients taking antifungal drugs.

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Active ingredient

Taurine

Composition

Tablets

Active substance:

Taurine250 mg;

Auxiliary substances:

MCC – 23 mg;

Potato starch – 18 mg;

Gelatin – 6 mg;

p> Colloidal silica (Aerosil) – 0.3 mg;

calcium stearate – 2.7 mg;

Pack of 60 pieces.