Cereton, 400 mg capsules 14 pcs

Pharmgroup:

Notropic.

Pharm Action:

Cereton is a nootropic. A central cholinostimulant that contains 40.5% metabolically protected choline. Metabolically protected promotes the release of choline in the brain.

Provides synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in the CNS, activates the reticular formation. It increases linear velocity of blood flow on the side of traumatic brain injury, promotes normalization of spatiotemporal characteristics of spontaneous bioelectrical activity of the brain, regress of focal neurological symptoms and restoration of consciousness; it has positive influence on cognitive and behavioral reactions of patients with cerebral vascular diseases (discirculatory encephalopathy and residual effects of cerebral circulatory disorders).

It has preventive and corrective effect on pathogenetic factors of involutional psychoorganic syndrome, changes the phospholipid composition of neuronal membranes and reduces cholinergic activity.

Stimulates dose-dependent release of acetylcholine under physiological conditions; participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, neuronal membrane plasticity, receptor function.
It has no effect on the reproductive cycle and has no teratogenic, mutagenic action.

Pharmacokinetics:

When parenteral administration (10 mg/kg) Cereton® predominantly accumulates in the brain, lungs and liver. Absorption is 88%, easily penetrates through the blood-brain barrier (when administered orally, the concentration in the brain is 45% of that in plasma).

The lungs excrete 85% of the drug as carbon dioxide, the remaining amount (15%) is excreted by the kidneys and through the intestine.

Indications

Active ingredient

Composition

1 capsule contains:

the active ingredient:

choline alphoscerate (in terms of 100% substance) 400 mg;

excipients:

Glycerol;

Purified water;

Capsule composition:

gelatin; sorbitol; glycerol; methyl parahydroxybenzoate; propyl parahydroxybenzoate; titanium dioxide; iron oxide yellow dye; purified water

How to take, the dosage

In the recovery period of craniocerebral trauma, ischemic or hemorrhagic stroke, Cereton in capsule form is prescribed 800 mg in the morning and 400 mg during the day for 6 months.

In chronic cerebrovascular insufficiency and dementia syndromes, Cereton is prescribed 400 mg (1 capsule) 3 times daily, preferably after meals, for 3-6 months.

Special Instructions

Cereton has no effect on the speed of psychomotor reactions.

Contraindications

Side effects

Nausea may occur (mainly as a consequence of dopaminergic activation), in which case the drug dose should be reduced.

Allergic reactions.

Solution for injection

Digestive system disorders: constipation, diarrhea, dry oral mucosa, pharyngitis.

Nervous system disorders: headache, drowsiness, insomnia, aggressiveness, anxiety, nervousness, cerebral ischemia, seizures, dizziness.

Skin disorders: rash, urticaria.

Others: pain at the site of injection, increased frequency of urination.

Overdose

Nausea may be noted. Treatment: symptomatic therapy.

Pregnancy use

The use of the drug Cereton during pregnancy and while breastfeeding is contraindicated.

Breastfeeding should be stopped during treatment with Cereton.

Similarities