Cerepro 250 mg/ml 4 ml, 3 pcs.

Pharmacological action

Cerepro is a central cholinostimulant containing 40.5% metabolically protected choline (metabolic protection promotes choline release in the brain).

On entering the body it is split by the action of enzymes into choline and glycerophosphate: choline is involved in the biosynthesis of acetylcholine – one of the main mediators of neural excitation; glycerophosphate is a precursor of phospholipids (phosphatidylcholine) of the neuronal membrane.

It provides synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and increases metabolic processes in the central nervous system, activates reticular formation.

It increases linear velocity of blood flow on the side of traumatic brain injury, promotes normalization of spatiotemporal characteristics of spontaneous bioelectrical activity of the brain; has a positive effect on the cognitive and behavioral responses of patients with cerebral vascular disease.

Cerepro improves brain function by acting on pathogenetic factors of involutional psychoorganic syndrome, changes phospholipid composition of neuronal membranes and reduces cholinergic activity.

Dose-dependently stimulates acetylcholine release; participating in the synthesis of phosphahydylcholine (membrane phospholipid), improves synaptic transmission, neuronal membrane plasticity, receptor function.

It has no effect on the reproductive cycle and has no teratogenic and mutagenic action.

Pharmacokinetics

Absorption – 88%), easily penetrates through the blood-brain barrier (when taken orally its concentration in the brain is 45%) of that in plasma.) It is excreted mainly by lungs as carbon dioxide (85%) and also by the kidneys and intestines (15%).

Indications

Active ingredient

Composition

1 ml of solution for intramuscular and intravenous administration contains:

the active ingredient:

250mg glycerylphosphorylcholine hydrate (choline alphoscerate);

supplementary substance:

water for injection.

How to take, the dosage

In acute conditions: intramuscularly or intravenously (slowly) at 1.0 g (1 ampoule) per day for 10-15 days, then switch to oral capsules at 0.8 g (2 capsules) in the morning and 0.4 g (1 capsule) during the day for 6 months.

In chronic conditions: orally 0.4 g (1 capsule) 3 times daily, preferably before meals.

The duration of treatment is 3-6 months.

Special Instructions

If nausea occurs after taking the drug, the dose should be reduced.

Cerepro has no effect on the speed of psychomotor reactions.

Contraindications

Hypersensitivity, pregnancy, breastfeeding.

Side effects

Allergic reactions, nausea (due to dopaminergic activation).

Similarities