Castor oil for oral administration 30 ml

When taken orally it is broken down by lipase in the small intestine to form ricinoleic acid, which irritates intestinal receptors throughout the intestine and stimulates peristalsis reflexively. The laxative effect usually comes after 5-6 hours. When taking castor oil there is also a reflex contraction of the uterine muscles.

Indications

Constipation, bowel preparation before diagnostic procedures.

Active ingredient

Common castor oil seeds

Composition

Castor Oil

How to take, the dosage

Inside. Adults take 15-30 grams (1-2 tablespoons) once a day. Children from 12 to 18 years a doctor prescribes the drug – 10-15 grams (1 dessert -1 tablespoon), once a day. Duration of use – no more than 3 days.

Interaction

When concomitant use reduces absorption of fat-soluble drugs – male fern extract, mebdazole, griseofulvin, probucol. Simultaneous use of saline laxatives may cause sharp intensification of laxative effect.

M-cholinoblocking drugs (atropine sulfate, platifylline, pirenzepine), antispasmodics (papaverine, drotaverine) weaken the effect of castor oil.

It enhances the effect of agents that stimulate contractile activity of the myometrium (methylergometrine, ergometrine, oxytocin, prostaglandins).

Special Instructions

The drug should not be used for more than 3 days; in case of no effect it is recommended to consult a physician. The drug does not affect potentially hazardous activities that require high concentration and speed of psychomotor reactions (driving vehicles, working with moving mechanisms.)
.

Contraindications

Hypersensitivity to the drug, “acute” abdomen, pregnancy, children under 12 years of age, poisoning with fat-soluble substances (phosphorus, benzene, etc.), treatment of worm infestation with male fern extract.

Side effects

Allergic reactions are possible. With long-term use – intestinal atony, hypovitaminosis A and D.

Overdose

It develops with ingestion of castor oil at a dose of 7 g/kg body weight. Characteristic symptoms: diarrhea, sharp spastic abdominal pain, impaired renal function, dizziness, hallucinations, loss of consciousness.

The specific antidotes are atropine sulfate and loperamide. Measures of care include withdrawal of the drug, replenishment of fluid and electrolyte losses (combined oral and intravenous administration is preferable), and symptomatic therapy aimed at eliminating the resulting disorders.

In case of development of neurotoxic effects, diapause 5-10 mg intravenously is administered.

Pregnancy use

Administration of the drug during pregnancy is contraindicated. If it is necessary to use the drug during lactation, breastfeeding should be stopped for the entire period of treatment.