Carboxym, 150 mg/ml, 1 ml, 10 pcs.

Name: Carboxym, 150 mg/ml, 1 ml, 10 pcs.
SKU: 224018
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EAN: 4602779001125 SKU: 224018 Categories: Medicine, Poisonings

Description

Carboxym belongs to the group of pyridinium cholinesterase reactivators. It has a pronounced antidote effect in the treatment of lesions with organophosphorus compounds (OPs).

The timely use of carboxime significantly accelerates the recovery of cholinesterase activity inhibited by PHOS.

It also has a positive effect on some other manifestations of poisoning (reduces bronchial spasm, motor disorders, etc.).

Carboxym has low toxicity and practically no cholinolytic effect.

Indications

The appearance of the initial signs of PHOS poisoning (agitation, miosis, salivation, etc.) when providing medical care, starting from the health center;
detection of reduced cholinesterase activity in persons under observation after staying in the focus of infection.

Carboxim is used against the background of antidotes (Atropine, Athene, P-10M) and other agents used in the treatment of poisoning with PHOS. After administration of the therapeutic antidote, carboxime is administered after 1-2 hours.

Active ingredient

Carboxym

Composition

1 ml of solution for intramuscular injection contains:

the active ingredient:

carboxime 150 mg,

auxiliary substances:

citric acid,

sodium hydroxide,

sodium chloride,

dinatrium edetate (trilon B),

water for injection.

How to take, the dosage
How to take, the dosage
Intramuscularly 1 ml. The total dose of carboxime used in the care depends on the severity of the lesion.
In case of mild FOS lesions (restlessness, miosis, salivation, sweating) after administration of cholinolytic-type drugs, carboxym is used in a single therapeutic dose. In some cases, it is possible to reintroduce the drug in the same dose.
In moderate FOS lesions (agitation, myofibrillation, bronchospasm, cyanosis, tachycardia, rarely bradycardia), a double administration of carboxime in a single therapeutic dose with an interval of 2-3 hours will usually be required.
In severe FOS lesions (seizures, coma, respiratory and cardiovascular failure), the dose of carboxime may be increased to 3-4 ml. This dose is administered in 1 ml of the drug at intervals of 1-2 hours. Treatment of affected FOS with carboxime in all cases is carried out with systematic
monitoring of cholinesterase activity.

Contraindications
Contraindications
There are no contraindications to the use of Carboxym if there are symptoms of PHOS intoxication.

Side effects
Side effects
In the recommended dose, Carboxym does not cause side effects. However, if high doses of Carboxym are used, there may be worsening of well-being, muscle weakness, dizziness, headache, nausea, and tachycardia.
Transient paresthesias may occur (mostly in the face).
The ECG may show phenomena of intracardiac conduction abnormalities and increased systolic rate. These phenomena soon go away and do not require additional treatment.
.

Additional information
Weight 0.035 kg
Shelf life
2 years
Conditions of storage
In a light-protected place, at a temperature not exceeding 20 °C
Manufacturer
FGUP Pharmzaschita NPC, Russia
Brand
FGUP Pharmzaschita NPC