Arutimol, eye drops 5 mg/ml 5 ml

Antiglaucoma drug of the group of non-selective beta-adrenoblockers.

Does not have intrinsic sympathomimetic and membrane stabilizing activity. When used topically as eye drops, it reduces both elevated and normal intraocular pressure by reducing the formation of intraocular fluid. It has no effect on accommodation, refraction and pupil size.

The action of the drug is seen 20 minutes after injection into the conjunctival sac. The maximum decrease of intraocular pressure (IOP) is reached within 1-2 hours and lasts for 24 hours.

Pharmacokinetics

Timolol maleate is slightly systemic absorbed when applied topically. After instillation of C _max thymolol in the aqueous humor of the anterior chamber of the eye is reached after 1-2 hours.

In a small amount enters the systemic bloodstream by absorption through the vessels of the conjunctiva, nasal mucous membranes and the lacrimal tract. It is excreted by the kidneys as metabolites.

In infants and young children, C _max timololol in plasma is greater than that in adult plasma.

Indications

Active ingredient

Composition

How to take, the dosage

Arutimol eye drops are applied in 1-2 drops 1-2 times a day.

After IOP stabilization the dose may be reduced to 1 drop 1 time/day.

Interaction

Special Instructions

Arutimol is prescribed with caution in patients with liver and kidney function abnormalities and diabetes mellitus.

For 30 minutes after injection, one should refrain from engaging in potentially hazardous activities requiring increased attention and rapid mental and motor reactions.

Persons should not wear soft contact lenses during treatment, and rigid lenses may be worn no earlier than 15 minutes after dosing.

When used together with beta-blockers, calcium channel blockers may cause excessive pressure reduction.

When using Arutimol at least once in 6 months one should control lacrimal function, corneal integrity and visual field.

Contraindications

The drug is used with caution in the following cases:

Side effects

Overdose

Symptoms: bradycardia, bronchospasm, dizziness, headache, arrhythmia, nausea, vomiting.

Treatment: flush eyes with water or saline; symptomatic therapy if necessary.

Pregnancy use

Arutimol is contraindicated in pregnancy, lactation and early childhood.

Similarities