Aqua Maris Plus, spray 30 ml

An anticongestive agent.

ATX code: R01AX10

Pharmacological properties

Aqua Maris® Plus is a sterile isotonic solution containing sea water and dexpanthenol. Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid, a water-soluble vitamin of the B complex, is a component of coenzyme A.

Dexpanthenol stimulates mucosal regeneration, normalizes cellular metabolism and has a regenerating and mild anti-inflammatory effect.

Injected into the nasal cavity, Aqua Maris® Plus moistens the mucous membrane, stimulates regeneration and has a trophic effect on the nasal mucous membrane cells.

The drug helps to thin mucus and normalize its production in bocalytic cells of the nasal cavity mucosa.

Micronutrients contained in the drug improve the function of the permeable epithelium which improves the resistance of the mucous membrane of the nasal cavity and sinuses to introduction of pathogenic bacteria and viruses.

Indications

Aqua Maris® Plus is indicated:

for the treatment and prevention of atrophic and subatrophic rhinitis;
for cleansing and moisturizing the nasal mucosa in inflammatory diseases of the nasal cavity, sinuses and nasopharynx, including pregnant women and during lactation;
in the complex therapy of allergic and vasomotor rhinitis (especially for persons predisposed or suffering from hypersensitivity to drugs, including pregnant women and during lactation);
for the prevention of nasal cavity infections in the autumn-winter period (including for pregnant women and during lactation);
patients suffering from dry nasal mucosa and persons living and working in rooms with air conditioning and/or central heating, in order to preserve the physiological characteristics of the nasal mucosa in altered microclimatic conditions;
people whose mucous membrane of the upper respiratory tract is constantly exposed to harmful influences (smokers, vehicle drivers, people working in hot and dusty workshops, as well as those living in regions with harsh climatic conditions);
for elderly people to prevent age-related atrophic changes in the nasal mucosa.

Pharmacological effect

Anticongestant.

ATX CODE: R01AX10

PHARMACOLOGICAL PROPERTIES

Aqua Maris® Plus is a sterile isotonic solution containing sea water and dexpanthenol. Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid, a water-soluble B complex vitamin, is a component of coenzyme A.

Dexpanthenol stimulates the regeneration of the mucous membrane, normalizes cellular metabolism, and has a regenerative and weak anti-inflammatory effect.

When injected into the nasal cavity, Aqua Maris® Plus moisturizes the mucous membrane, stimulates regeneration and has a trophic effect on the cells of the nasal mucosa.

The drug helps to liquefy mucus and normalize its production in the goblet cells of the nasal mucosa.

The trace elements included in the drug improve the function of the ciliated epithelium, which increases the resistance of the mucous membrane of the nasal cavity and paranasal sinuses to the introduction of pathogenic bacteria and viruses.

Special instructions

It is not recommended to use it outdoors during the cold season; it is not recommended to go outside from a warm room immediately after using the drug in the cold season.

ABILITY TO INFLUENCE REACTION SPEED WHEN DRIVING VEHICLES OR WORKING WITH OTHER MECHANISMS

The drug does not affect the ability to drive vehicles and machinery.

Composition

Active ingredient:

Adriatic Sea water – 25 g.

Excipients:

dexpanthenol 75 L (not less than 75% dexpanthenol)* – 1.33 g;

purified water – 73.67 g.

*Dexpanthenol 75L is an aqueous solution containing at least 75% (R)-panthenol, stabilized with approximately 1% D-pantolactone.

Does not contain preservatives.

Presence of ions:

Na+ – min. 1.90 mg/ml; Ca2+ – min. 0.06 mg/ml; Mg2+ – min. 0.25 mg/ml; Cl- – min. 4.10 mg/ml; SO4 2– – min. 0.45 mg/ml; HCO3 – – min. 0.025 mg/ml.

Pregnancy

Pregnancy and breastfeeding are not contraindications for use.

Contraindications

Hypersensitivity to the components of the drug.

Side Effects

Allergic reactions are possible.

Interaction

Since the drug does not have a systemic effect on the body, no interactions with other drugs have been noted.

May be used with other medications used to treat runny nose.

Overdose

No cases of overdose have been reported.

Storage conditions

At a temperature not exceeding 25 °C.

Shelf life

2 years.

Manufacturer

JADRAN-GALENSKI LABORATORY j.s., Croatia