Amiodarone, tablets 200 mg 30 pcs

Name: Amiodarone, tablets 200 mg 30 pcs
SKU: 294154
Availability: InStock

€4.28

EAN: 4810201006314 SKU: 294154 Categories: Arrhythmia remedies, Cardiovascular, Medicine

Description

Class III antiarrhythmic drug (repolarization inhibitor). It also has antianginal, coronary dilation, alpha- and beta-adreno-blocking and antihypertensive effects.

Indications

Myocardial infarction, Arrhythmia, Heart palpitations
Relapse prevention

Active ingredient

Amiodarone

How to take, the dosage

The drug should only be taken as prescribed by your doctor!

Interaction

Contraindicated combinations: risk of pirouette-type polymorphic ventricular tachycardia (arrhythmia characterized by polymorphic complexes that change the amplitude and direction of ventricular excitation conduction relative to the isoline (electrical heart systole): Class IA antiarrhythmic agents (quinidine, hydroquinidine, disopyramide, procainamide), Class III (dofetilide, ibutilide, bretilium tozilate), sotalol; bepridil, vincamine, phenothiazines (chlorpromazine, cyamemazine, levomepromazine, thioridazine, trifluoperazine, fluphenazine), benzamides (amisulpride, sultoprid, sulpiride, thiapride, veraliprid), butyrophenones (droperidol, haloperidol), sertindol, pimozide tricyclic antidepressants, cisapride, macrolides (erythromycin IV, spiramycin), azoles, antimalarials (quinine, chloroquine, mefloquine, halofantrine, lumefantrine); pentamidine (parenteral), difemanil methylsulfate, misolastine, astemizol, terfenadine, fluoroquinolones (incl.including moxifloxacin).
Unrecommended combinations: beta-adrenoblockers, blockers of “slow” calcium channels (verapamil, diltiazem) – risk of impaired automatism (marked bradycardia) and conduction; laxatives stimulating peristalsis – risk of ventricular tachycardia “pirouette” against hypokalemia caused by laxatives.

Combinations requiring use with caution: diuretics causing hypokalemia, amphotericin B (intravenous), systemic glucocorticosteroids, tetracosactide – risk of ventricular arrhythmias, including ventricular tachycardia.procainamide – risk of procainamide side effects (amiodarone increases plasma concentration of procainamide and its metabolite -N-acetylprocainamide).

Special Instructions

Caution should be exercised when prescribing the drug to patients with heart failure, liver disease, hypokalemia, porphyria, elderly patients.

Contraindications

– Hypersensitivity to iodine, amiodarone or excipients of the drug.
– Lactose intolerance (lactase deficiency), glucose-galactose malabsorption syndrome (the drug contains lactose).
– Syndrome of sinus node weakness (sinus bradycardia, sinoatrial block), except for their correction with an artificial pacemaker (danger of sinus node “stop”).
– II-III degree atrioventricular block, in the absence of an artificial pacemaker.
– Hypokalemia and hypomagnesemia.
– Combination with agents that can prolong QT interval and cause paroxysmal tachycardia, including ventricular “pirouette” tachycardia (see “Interaction with other organs”). Interaction with other drugs):
– antiarrhythmic drugs: Class IA (quinidine, hydroquinidine, di-zopyramide, procainamide); Class III antiarrhythmic drugs (dofetilide, ibutilide, brettilia tozilate); sotalol;
– other (non antiarrhythmic) drugs, such as bepridil; vincamine; some neuroleptics: phenothiazines (chlorpromazine, cyamemazine, levomepromazine, thioridazine, trifluoperazine, fluphenazine), benzamides (amisulpride, sultopride, sulpride, thiapride, veralipride), butyrophenones (droperidol, haloperidol), sertindol, pimozide; cisapride; tricyclic antidepressants macrolide antibiotics (in particular erythromycin in intravenous administration, spiramycin); azoles; antimalarials (quinine, chloroquine, mefloquine, halofantrine); pentamidine in parenteral administration; difemanil methylsulfate; misolastine; astemizole, terfenadine; fluoroquinolones.
– Congenital or acquired prolongation of QT interval.
– Thyroid dysfunction (hypothyroidism, hyperthyroidism).
– Interstitial lung disease.
– Pregnancy (see “Administration during pregnancy and lactation”). “Application in pregnancy and during lactation.
– Lactation period (see “Application in pregnancy and during lactation”).
– Age under 18 years (effectiveness and safety is not established).

Side effects

Frequency: very common (10% or more), common (1% or more; less than 10%), infrequent (0.1% or more; less than 1%), rare (0.01% or more; less than 0.1%), very rare (less than 0.01%, including individual cases), frequency unknown (no data available to determine frequency).

Overdose

Symptoms: bradycardia, AV-blockade, pirouette-type ventricular tachycardia, pirouette-type paroxysmal tachycardia, exacerbation of symptoms of existing CHF, liver failure, cardiac arrest.

Similarities

Cordarone, Amiodarone

Additional information

Weight	0.020 kg
Shelf life	2 years.
Conditions of storage	In the dark place at the temperature not more than 25 °С. Keep out of reach of children.
Manufacturer	Borisov Medical Preparations Plant, Belarus
Medication form	pills
Brand	Borisov Medical Preparations Plant