Ambene Bio, 2 ml 5 pcs

Pharmacotherapeutic group: tissue repair stimulator of natural origin.

ATX code: M09AX

Pharmacological properties

AMBENE® Bio is a chondroprotector, the active component of which is bioactive extract from small marine fish. The extract contains mucopolysaccharides (chondroitin sulfate), amino acids, peptides, ions of sodium, potassium, calcium, magnesium, iron, copper and zinc.

AMBENE® Bio prevents the destruction of the macromolecular structures of normal tissue, stimulates repair processes in the interstitial tissue and articular cartilage tissue, which explains its analgesic effect. The anti-inflammatory effect and tissue regeneration are based on inhibition of hyaluronidase activity and normalization of hyaluronic acid biosynthesis. Both these effects are synergistic and cause activation of regenerative processes in tissues (in particular restoration of cartilage structure).

Indications

AMBENE® Bio is used in adults for primary and secondary osteoarthritis of different localization (coxarthrosis, gonarthrosis, arthrosis of small joints), osteochondrosis and spondylosis.

Active ingredient

Concentrated extract from small marine fish

Composition

Bioactive extract from small marine fish – 1.0 ml includes: Active ingredient: concentrated extract from small marine fish – 0.1 g/ml Excipients: phenol – up to 0.005 g/ml; water for injections up to 1.0 ml

How to take, the dosage

In polyosteoarthritis and osteochondrosis the drug is injected deeply intramuscularly 1 ml per day. The course of treatment is 20 injections (1 injection per day for 20 days). If large joints are affected predominantly, the drug is injected intraarticularly with 1-2 ml in each joint at intervals of 3-4 days. A total of 5-6 injections into each joint. A combination of intraarticular and intramuscular injection method is possible. It is advisable to repeat the treatment course in 6 months after medical consultation.

Special Instructions

In case of individual intolerance of seafood (sea fish), the risk of allergic reactions increases. Effect on the ability to drive vehicles and mechanisms There are no data on adverse effects of the drug on the ability to drive vehicles and mechanisms.

Synopsis

Colorless or light yellow to light brownish-yellow liquid.

Contraindications

Hypersensitivity to the components of the drug.

Pregnancy and lactation.

Children’s age.

Cautions

Prescribing the drug in adolescents is not recommended because of the lack of scientific clinical data in this patient population.

Side effects

The frequency of adverse reactions below was determined according to the following grading: very common (>1/10), common (>1/100, ≤1/10), infrequent (>1/1000, ≤1/100), rare (>1/10000, ≤1/1000), very rare (≤1/10000). Allergic reactions: rare – itching; very rare – anaphylactic reactions. Local: rarely – redness of the skin and burning sensation at the site of drug administration. Other: transient myalgia. In some cases with intraarticular injections, a transient increase in pain syndrome is possible.

Overdose

Allergic reactions (sometimes severe) may occur in overdose in predisposed patients.

Pregnancy use

AMBENE® Bio is contraindicated in pregnancy. If it is necessary to use the drug during lactation, breastfeeding should be stopped.