Akriderm GC, 0.05%+0.1%+1% cream 15 g

Acriderm GC is a combined drug with anti-inflammatory, anti-allergic, antibacterial and antifungal (fungicidal) effect.

Gentamicin is a broad-spectrum antibiotic of the group of aminoglycosides, has a bactericidal effect. Highly susceptible gram-negative microorganisms – Proteus spp. (in-positive and indo-positive), Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp., Staphylococcus spp. (methicillin-resistant). Sensitive: Enterococcus faecalis, Serratia spp., Pseudomonas spp., Acinetobacter spp., Citrobacter spp. Resistant: Neisseria meningitidis, Treponema pallidum, anaerobic microbes: Streptococcus spp. (except Streptococcus pneumoniae), Enterococcus faecalis; Providencia rettgeri.

Betamethasone is a glucocorticosteroid that has local anti-inflammatory, anti-edema, anti-allergic effects.

Clotrimazole is an antifungal agent from the group of imidazole derivatives for topical use. It acts by disrupting the synthesis of ergosterol, which is a part of the cell membrane of fungi. It has a wide spectrum of action. It is active against pathogenic dermatophytes (Trichophyton rubrum, Trichophyton mentagro- phytes, Epidermophyton floccosum, Microsporum canis), yeasts and molds (Candida spp., Torulopsis glabrata, Rhodotorula spp., Pityrosporum orbiculare).

Indications

– Simple and allergic dermatitis (especially complicated by secondary infection);

– diffuse neurodermatitis (including atopic dermatitis);

– circumscribed neurodermatitis (including simple chronic lichen.

– dermatomycosis (dermatophytosis, candidiasis, herpes simplex), especially if localized in the groin area and large skin folds.

Active ingredient

Composition

1 g contains:

Betamethasone dipropionate 0.64 mg.

Auxiliary substances:

nipagine;

solid paraffin;

vaseline;

p> propylene glycol;

vaseline medical oil;

cetostearyl alcohol emulsifying type A or Lanette SX type emulsifying wax;

dinatrium ethylenediaminetetetraacetic acid salt (trilon B);

Sodium sulfite 7-water;

purified water.

How to take, the dosage

For outside use.

Acriderm GC cream is applied to the affected areas of the skin, rubbing gently, a small amount twice a day. The duration of treatment is determined individually and depends on the nosological form and severity of the disease. With dermatomycosis of feet average duration of treatment is 2-4 weeks. If clinical improvement does not occur soon, it is necessary to specify the diagnosis or change the treatment regimen.

Interaction

Interaction of Acriderma GC with other drugs has not been established.

Special Instructions

Eye contact should be avoided.

In case of resistant bacterial or fungal microflora the drug should be withdrawn, appropriate therapy should be prescribed.

Because of the fact that children have a larger skin surface area relative to their body weight than adults and also their epidermis is underdeveloped, when the drug is applied topically more active substances can be absorbed and therefore there is a higher risk of systemic side effects.

The drug should be used as briefly as possible in children and with all precautions taken.

Contraindications

– Hypersensitivity to any of the ingredients of the drug;

– Tuberculosis of the skin;

– Cutaneous manifestations of syphilis;

– Varicella pox;

– herpes simplex;

– postvaccination skin reactions;

– open wounds;

– childhood (under 2 years).

Side effects

Itching, burning, irritation, dry skin, folliculitis, hypertrichosis, steroid acne, hypo-pigmentation, allergic reactions.

When using occlusive dressings – maceration, infection, skin atrophy, stretch marks, sweating.

In case of long-term treatment or application over a large surface area – development of systemic side effects: weight gain, osteoporosis, increased blood pressure, edema, gastrointestinal mucosal ulceration, exacerbation of latent foci of infection, hyperglycemia, agitation, insomnia, dysmenorrhea.

Overdose

Symptoms:phenomena of hypercorticism.

Treatment:gradual withdrawal of the drug. Symptomatic therapy. If necessary, correction of electrolyte abnormalities.

Pregnancy use

During pregnancy (especially in the first trimester) topical application of the ointment in pregnant women is allowed only in cases when the estimated benefit to the mother exceeds the potential risk to the fetus. In such cases, the use of the drug should be of short duration and limited to small areas of the skin.

It is not known whether the components of the drug are excreted with the breast milk. Therefore, when prescribing Acriderm GC ointment during lactation, it is recommended to stop breastfeeding.

Similarities