Afrin, moisturizing spray 0.05% 15 ml

Alpha-adrenergic stimulant for topical use.

It has a vasoconstrictor effect. Oxymetazoline causes vasoconstriction of mucous membranes of the nose, sinuses and eustachian tube which leads to reduction of their edema and release of nasal breathing in allergic and/or infectious-inflammatory rhinitis (runny nose).

With the presence of excipients in the composition of the drug (microcrystalline cellulose and sodium carmellose and povidone-K29-32) Afrin® moistening nasal spray does not leak from the nose and does not run down the throat because after injection into the nasal passages the spray becomes more viscous and is held on the nasal mucosa more effectively than the standard water solution.

This medication contains humectants (glycerol and macrogol – 1450) to help retain moisture, which helps provide hydration to dry or irritated nasal mucosa. According to clinical studies, the drug starts working within 1 minute and the action lasts up to 12 hours.

Indications

Sinusitis, Flu, Allergic rhinitis, Runny nose (rhinitis), Nasal congestion, Colds, Otitis media

Symptomatic treatment of rhinitis (runny nose) of allergic and/or infectious-inflammatory etiology, sinusitis, eustachianitis, hay fever.

Active ingredient

Oxymetazoline

Composition

Active ingredient:

oxymetazoline hydrochloride 0.5 mg.

Auxiliary substances:

Microcrystalline cellulose and sodium carmellose (Avicel RC-591) 30 mg,

sodium hydrophosphate 0.975 mg,

sodium dihydrophosphate monohydrate 5.525 mg,

disodium edetate dihydrate 0.3 mg,

macroGol-1450 50 mg,

povidone-K29-32 30 mg,

benzyl alcohol 2.5 mg,

lemon flavoring 1.5 mg,

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benzalkonium chloride solution 17% 1.471 mg,

glycerol 5 mg,

purified water q.s. to 1 ml.

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How to take, the dosage

Intranasally. Shake the spray bottle vigorously before each use.

Before the first use of the nasal spray it is necessary to “calibrate” it by pressing the head of the sprayer several times.

Adults and children over 6 years of age – 2-3 injections into each nasal passage at 10-12 hour intervals.

The frequency of application can be increased up to 3 times a day in adults.

It is not recommended to exceed the stated dose.

Interaction

Slows absorption of local anesthetic drugs, prolongs the time of their action.

Co-use with other vasoconstrictor drugs increases the risk of side effects.

Concomitant use of monoamine oxidase inhibitors (including a period of 14 days after their withdrawal), maprotiline and tricyclic antidepressants increases blood pressure.

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Special Instructions

In prolonged use (more than one week), nasal congestion symptoms may resurface.

If it is necessary to continue treatment for more than 5 days, it is necessary to consult a doctor.

Contact with the drug in the eyes should be avoided.

The drug, when used correctly and in the recommended doses, has no effect on driving and operating machinery,

But if side effects such as dizziness occur, these activities should be avoided.

Synopsis

Afrin Moisturizing is a modern remedy for runny nose in the form of a spray with a patented formula, thanks to which it is fixed on the nasal mucosa, acting in the epicenter of congestion from the 1st minute

Contraindications

Hypersensitivity to sympathomimetic agents, to any component of the drug, atrophic rhinitis, concomitant use of monoamine oxidase inhibitors (including a period of 14 days after their withdrawal), children under 6 years of age.

With caution

Coronary artery disease, arrhythmias, chronic heart failure, marked atherosclerosis, arterial hypertension, hyperthyroidism, diabetes mellitus, chronic renal failure, closed-angle glaucoma, prostatic hyperplasia with clinical symptoms, pregnancy, lactation period.

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Side effects

In general, the drug is well tolerated, and possible adverse events are usually mild and transient.

Transient dryness and burning of the nasal mucosa, dry mouth and throat, sneezing; increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, palpitations, sleep disorders.

In long-term use – tachyphylaxis, reactive hyperemia and atrophy of the nasal mucosa. Benzalkonium chloride, which is part of the drug, may cause localized skin reactions.

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Overdose

In case of significant overdose or accidental ingestion nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, increased blood pressure, shortness of breath, mental disorders, central nervous system depression (drowsiness, decreased body temperature, bradycardia, decreased blood pressure, respiratory arrest and coma) are possible.

The treatment is symptomatic.

In case of accidental ingestion – gastric lavage, activated charcoal. Vasopressor drugs are contraindicated.

Similarities

Nasivin, Nasol, Otrivin, Nasol Advance, Nasivin Sensitive, Rinostop, Nesopin, Oxyfrin, Sialor, Rinostop Extra, Cold and Flu, No Time to Be Sick