🐾 Xylanite solution 2%, bottle 50 ml

Xylazine hydrochloride, a component of Xylanit, is an antagonist of central α2-adrenoreceptors, has sedative, myorelaxative and analgesic effects, stimulates both central and peripheral alpha-receptors. When parenteral administration it causes rapid onset of dissociated anesthesia. After intramuscular or subcutaneous administration, Xylanit takes 5 to 20 minutes to take effect, after intravenous administration – 1 to 5 minutes. The duration of sedative action varies in cattle from 30 minutes to 5 hours, in horses – from 30 minutes to 1 hour, in small domestic animals – from 1 to 2 hours. Analgesic effect lasts for 45 minutes in cattle, 15 to 30 minutes in small animals, in horses the duration varies from 5 to 20 minutes, depending on the dosage and the individual sensitivity of the body. Myorelaxation effect in animals comes after 20 to 50 minutes. Xylazine hydrochloride increases the effect of tranquilizers, catalepsics and anesthetics, therefore it must be used with caution in combination with the drugs of these groups. Xylazine hydrochloride is a moderately hazardous substance according to the degree of its effect on the body of warm-blooded animals; in the recommended doses it has no local irritating and sensitizing effect.

Indications

Active ingredient

Composition

How to take, the dosage

Xylanit is administered to animals intramuscularly or intravenously (slowly, within 1 – 2 minutes). In cattle, xylanit is administered intramuscularly depending on indications at a dose of 0.25 – 1.5 ml per 100 kg of animal weight, which corresponds to 0.05 – 0.3 mg of xylazine hydrochloride per 1 kg of animal weight. Depending on the applied dose of Xylazine, the animal experiences sedation and myorelaxation of varying degrees:

In small cattle, xylanit is administered intramuscularly depending on indications at a dose of 0.05 – 0.25 ml of the drug per 10 kg of animal weight, corresponding to 0.1 – 0.5 mg xylazine hydrochloride per 1 kg of animal weight. Horses are intravenously injected with the dose 7,5 – 15,0 ml per 100 kg of the animal weight, which corresponds to 0,15 – 0,3 mg of xylazine hydrochloride per 1 kg of the animal weight or 3,0 – 5,0 ml per 100 kg of the animal weight, which corresponds to 0,6 – 1,0 mg of xylazine hydrochloride per 1 kg of the animal weight slowly and intravenously depending on the indications and type of the animal higher nervous activity. Sedation usually occurs within 5 minutes after injection and lasts about 20 minutes. Easily excitable animals shall be administered the drug in maximum dose; it is not recommended to administer the drug in dorsal position of the animal. In dogs during manipulations not accompanied by painful manifestations, xylanit is administered intramuscularly in the dosage of 0.5 – 1.0 ml per 10 kg of animal weight, which corresponds to 1 – 2 mg of xylazine hydrochloride per 1 kg of animal weight. In cats – intramuscularly or subcutaneously at the rate of 0.15 ml of the drug per 1 kg of cat weight, which corresponds to 3 mg of xylazine hydrochloride per 1 kg of animal weight. In case of painful manipulations, combined use of Xylarinum with other drugs (barbiturates, analgesics or local anesthetics) is recommended. Anesthesia with barbiturates should be performed 20 minutes after the administration of Xylanit, i.e. after deep sedation has been achieved. Under these conditions, the dosage of barbiturates should be reduced by a factor of two or three. Animals should not be disturbed until the full effects of Xylanit are achieved. If the required depth of sedation is not achieved, additional injections to achieve the desired effect are not recommended. Re-injection of Xylanit at a higher dose is possible after 24 hours, after the full recovery of the animal’s physiological state. Animals should be kept under observation until their physiological state is fully recovered. When Xylanit is used in combination with cataleptic and anesthetic drugs, their dosage should be reduced by a factor of two or three from that specified in the instructions for use.

Special Instructions

Contraindications

Side effects