Zinerit, 30 ml
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Pharmacological action – comedonolytic, antimicrobial, anti-inflammatory.
Eritromycin causes a bacteriostatic effect. Zinc stabilizes cell membranes, has astringent, anti-inflammatory and antiseptic effects, reduces the production of sebum secretion.
Pharmacodynamics
Eritromycin acts bacteriostatically on the microorganisms that cause acne: Propionibacterium acne and Streptococcus epidermidis. Zinc reduces the production of sebum secretion and has an astringent effect.
Pharmacokinetics
The complex bonding of the ingredients of the product ensures good penetration of the active ingredients into the skin. Zinc is mainly bound to the follicular epithelium and is not resorbed into the systemic bloodstream.
A small portion of erythromycin is systemically distributed and subsequently eliminated from the body.
Indications
Acne treatment.
Pharmacological effect
Pharmacological action – comedolytic, antimicrobial, anti-inflammatory.
Erythromycin causes a bacteriostatic effect. Zinc stabilizes cell membranes, has an astringent, anti-inflammatory and antiseptic effect, and reduces the production of sebaceous gland secretions.
Pharmacodynamics
Erythromycin has a bacteriostatic effect on microorganisms that cause acne: Propionibacterium acne and Streptococcus epidermidis. Zinc reduces the production of sebaceous gland secretions and has an astringent effect.
Pharmacokinetics
The complex connection of the drug components ensures good penetration of the active substances into the skin. Zinc is primarily bound to the follicular epithelium and is not resorbed into the systemic circulation.
A small part of erythromycin undergoes systemic distribution and is subsequently excreted from the body.
Special instructions
When using the drug, cross-resistance to other macrolide antibiotics, lincomycin, and clindamycin may occur.
It is necessary to avoid getting the drug in the eyes or on the mucous membrane of the mouth and nose, because this may cause irritation and burns.
Active ingredient
Zinc acetate, Erythromycin
Composition
Active ingredients:
erythromycin;
zinc acetate dihydrate micronized;
Solvent:
diisopropyl sebacate,
ethanol
Contraindications
Hypersensitivity to zinc or other components of the drug
Side Effects
Local reactions – burning sensation, irritation, dry skin.
As a rule, these reactions are mild and do not require discontinuation of the drug and/or symptomatic therapy.
Interaction
To date, no clinically significant interactions of Zinerit with other drugs have been established.
Storage conditions
At 15–25 °C
Shelf life
3 years
Manufacturer
LEO PHARMA AS, Denmark
Shelf life | 3 years |
---|---|
Conditions of storage | At 15-25 °C |
Manufacturer | Astellas Pharma Europe B.V., Netherlands |
Medication form | solution for external use |
Brand | Astellas Pharma Europe B.V. |
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