Zalain, 2% cream 20 g

ATC code: D01AС14

Pharmacological properties

Sertaconazole is an imidazole derivative for topical use with a broad spectrum of action against pathogenic fungi (Candida albicans, C. Tropicalis, C. spp, Pityrosporum orbiculare), dermatophytes (Trichophyton, Epidermophyton and Microsporum) and pathogens of skin and mucous membrane infections (gram-positive strains of staphylococci and streptococci).

The mechanism of action of sertaconazole is inhibition of ergosterol synthesis, the main sterol of fungal and yeast membranes, and increase of cell membrane permeability, which leads to lysis of the fungus cell.

Pharmacokinetics

Sertaconazole nitrate is undetectable in blood and urine when used topically.

Indications

Skin fungus, Skin itching

Topical treatment of superficial skin mycoses: dermatomycoses, Tinea pedis (athlete’s foot), Tinea crusis, Tinea corporis, Tinea barbae (beard mycosis), Tinea manus, candidiasis (Monolisiasis), and Pityiriasis versicolor (Pityrosporum orbiculare).

Active ingredient

Sertaconazole

Composition

1 g of the cream contains 20 mg of the active ingredient – sertaconazole nitrate, as well as excipients:

ethylene glycol and polyethylene glycol palmitostearate,

polyglycolized saturated glycerides,

glycerin isostearate,

paraffin oil,

methyl p-hydroxybenzoate ,

sorbic acid,

purified water.

How to take, the dosage

The cream is applied to the affected areas of the skin in an even thin layer twice a day, overlapping about 1 cm of the surface of healthy skin.

The duration of treatment depends on the etiology of the causative agent and the localization of the infection. As a rule, symptoms disappear after 2-4 weeks. The recommended duration of treatment is 4 weeks.

Contraindications

Hypersensitivity to antifungal agents (imidazole derivatives) or excipients of the cream.

Side effects

Contact dermatitis.

Local erythematous reactions may disappear quickly, which does not require discontinuation of the drug.

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Similarities

Oflomikol