Xanthinol nicotinate, 150 mg/ml 2 ml 10 pcs.

The drug combines properties of theophylline and nicotinic acid: causes dilation of peripheral vessels, improves collateral circulation, improves oxygenation and tissue nutrition, increases oxidative phosphorylation and ATP synthesis.

Xanthinol nicotinate improves cerebral blood circulation and reduces cerebral hypoxia.

The drug also activates the processes of fibrinolysis and reduces platelet aggregation.

Indications

– obliterating atherosclerosis;

– endarteritis of the vessels of the lower extremities;

– diabetic angiopathy;

– retinopathy;

– acute thrombophlebitis of superficial and deep veins;

— postthrombophlebitic syndrome;

– trophic ulcers of the lower extremities:

– bedsores;

– Meniere’s syndrome;

– dermatoses associated with vascular trophic disorders;

– cerebrovascular accident.

Pharmacological effect

The drug combines the properties of theophylline and nicotinic acid: it causes dilation of peripheral blood vessels, improves collateral circulation, improves oxygenation and tissue nutrition, enhances oxidative phosphorylation and ATP synthesis.

Xanthinol nicotinate improves cerebral circulation and reduces cerebral hypoxia.

The drug also activates fibrinolysis processes and reduces platelet aggregation.

Special instructions

Xanthinol nicotinate causes a nicotine-like syndrome, accompanied by hyperesthesia of the mucous membrane of the nose and mouth (exacerbates the sensitivity of the olfactory and taste receptors); therefore, the smell and taste of alcoholic beverages taken during therapy is perceived as sharper and perverted.

Avoid contact of the solution with the eyes or mucous membranes.

Impact on the ability to drive vehicles and operate machinery

Large doses of the drug can cause dizziness, weakness and arterial hypotension; therefore, you should refrain from driving a vehicle or operating machinery.

Active ingredient

Xanthinol nicotinate

Composition

1 ml xanthinol nicotinate 150 mg

Excipients:

d/i water (up to 1 ml).

Contraindications

– acute heart failure, incl. acute myocardial infarction;

— chronic heart failure IIB-III degree;

– mitral stenosis;

– arterial hypotension;

– acute bleeding;

– peptic ulcer of the stomach and duodenum in the acute stage;

– acute renal failure;

– glaucoma;

– children’s age;

— pregnancy first trimester;

– increased individual sensitivity to the components of the drug.

Side Effects

Xanthinol nicotinate can cause dizziness, decreased blood pressure, general weakness, a feeling of heat, tingling and redness of the skin of the upper body, especially the neck and head, nausea, anorexia, and diarrhea.

These symptoms usually disappear after 10-20 minutes and do not require special treatment or cessation of therapy with this drug.

If undesirable effects that are not described in these instructions occur, or if the above side effects increase during therapy with this drug, you should immediately inform your doctor.

With long-term administration in high doses, the drug causes changes in glucose tolerance, increased activity of liver transaminases, alkaline phosphatase, and hyperuricemia.

Interaction

To avoid a sharp decrease in blood pressure, the drug should not be used simultaneously with antihypertensive drugs.

Cannot be combined with therapy with MAO inhibitors, strophanthin.

Overdose

The drug is low toxic.

Symptoms: acute overdose of xanthinol nicotinate is accompanied by arterial hypotension, general weakness, dizziness, tachycardia, abdominal pain and vomiting.

Treatment: when symptoms of overdose appear, symptomatic therapy is prescribed.

Manufacturer

Armavir pharmacy base, Russia