Viferon, gel 36000 me/g 12 g

Interferon alpha-2b human recombinant has immunomodulatory, antiviral and antiproliferative properties. It suppresses replication of RNA- and DNA-containing viruses. Immunomodulatory properties of interferon such as increased phagocytic activity of macrophages, increased specific cytotoxicity of lymphocytes to target cells determine its mediated antibacterial activity.

In the presence of antioxidants alpha-tocopherol acetate, citric and benzoic acids increases specific antiviral activity of interferon and its immunomodulatory effect, which increases the effectiveness of the body’s own immune response to infectious agents.

The preparation has a pronounced local immunomodulatory effect and promotes increase of locally produced antibodies of class secretory IgA which prevent fixation and reproduction of pathogenic microorganisms on mucous membranes and this provides prophylactic effect of the preparation for prevention of viral and other diseases.

The gel base provides prolonged action of the drug. The antioxidants contained in the dosage form – alpha-tocopherol acetate, citric and benzoic acids possess anti-inflammatory, membranostabilizing and regenerating properties, and also help to save the biological activity of human recombinant interferon alpha-2b.

Indications

Prevention of flu and colds, herpes, influenza

• – in treatment of ARI, including influenza, frequent and prolonged ARI, including those complicated by bacterial infection
  – prevention of ARI, including influenza;
  – in treatment of recurrent stenotic laryngotracheobronchitis;<
  – prevention of recurrent stenotic laryngotracheobronchitis;
  – in treatment of acute and exacerbations of chronic recurrent herpes infections of skin and mucous membranes, including urogenital form of herpes infections;
  – in treatment of herpes cervicitis.

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Active ingredient

Interferon alfa-2b

Composition

1 g of gel for topical and external use contains the active ingredient:

interferon alpha-2b human recombinant 36000 IU;

excipients:

alpha-tocopherol acetate 0.055 g,

benzoic acid 0.00128 g,

sodium tetraborate decahydrate 0.0018 g,

methionine 0.0012 g,

citric acid monohydrate 0.001 g,

Sodium chloride 0.004 g,

Human serum albumin 10% solution 0.02 g,

distilled glycerin (glycerol) 0.02 g,

sodium carmellose 0.02 g,

ethanol 95% 0.055 g,

water purified to 1 g.

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How to take, the dosage

The drug is used topically and topically.

In the complex treatment of acute respiratory infections, including influenza, long and frequent acute respiratory infections, including those complicated by bacterial infection:

A strip of gel not more than 0.5 cm in length is applied to the pre-dried surface of the nasal mucosa and/or the surface of the palatine tonsils 3-5 times a day. Course duration is 5 days, if necessary, the course can be extended.

Recurrent stenotic laryngotracheobronchitis:

A strip of gel not more than 0.5 cm in length is applied to the surface of the palatine tonsils in the acute period of the disease 5 times a day. The course duration is 5-7 days.

The gel strip not more than 0.5 cm in length is applied to the surface of the palatine tonsils after the acute period of the disease 3 times a day. The course duration is 3 weeks.

Acute and chronic recurrent herpetic infection (at the appearance of the first signs of the disease or in the period of precursors):

A strip of gel not more than 0.5 cm in length is applied with a spatula or cotton swab/ cotton swab to the pre-dried affected surface 3-5 times a day. Course duration is 5-6 days. If necessary, the duration of the course is increased until the clinical manifestations disappear.

Herpetic cervicitis:

1 ml of gel is applied with a cotton swab to the pre-cleared surface of the cervix 2 times a day. Course duration is 7 days. If necessary, the course can be extended up to 14 days.

RTI, including flu:

In the period of rising of the disease a strip of gel not more than 0.5 cm in length is applied to the pre-dried surface of the nasal mucosa and/or the surface of the palatine tonsils 2 times a day. Course duration is 2-4 weeks.

Recurrent stenotic laryngotracheobronchitis:

A strip of gel not more than 0.5 cm in length is applied to the surface of the palatine tonsils using a spatula or cotton swab/ cotton swab 2 times a day. Course duration is 3-4 weeks, the courses are repeated twice a year.

The gel is applied to the nasal mucosa after cleaning the nasal passages, on the surface of the palatine tonsils – in 30 minutes after eating. When applying the gel on the palatine tonsils do not touch the tonsils with a cotton swab, but only with the gel, the gel flows down the surface of the tonsil on its own. When applying the gel on the cervix, you should first remove mucus and secretions from the vaginal fornix and cervix with a cotton or gauze swab.

If the gel is applied to the affected areas of the skin and mucous membranes, after 30-40 minutes a thin film is formed on which the product is applied again. If desired the film can be peeled off or washed off with water before reapplying the product.

Interaction

The drug combines well with all medications used in the treatment of the above diseases (antibiotics, chemopreparations, glucocorticosteroids).

Special Instructions

There are no age restrictions for the use of the drug in the form of a gel according to the indications and in the recommended doses.

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Contraindications

Hypersensitivity to any of the ingredients of the drug.

Side effects

In rare cases, allergic reactions (skin rashes, itching) may occur.

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Pregnancy use

Pregnancy and lactation are not contraindications to the use of the drug due to the very low absorption of the components.

Do not use on the nipple and areola area during lactation.

Similarities

Infagel, Grippferon, Reaferon-EC, Reaferon-EC-Lipint, Laifferon